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Johns Hopkins Mini-Brains Reveal Variable Alzheimer's Drug Responses
Johns Hopkins researchers grew hundreds of mini-brain organoids from Alzheimer's patients' cells and found that some responded to a common antidepressant while others did not — patterns and vesicle-ba
STAT+: ‘Cochlear implant for blindness’ debuts in Europe, could launch in U.S. in 2027
Science Corporation's retinal implant, designed to partially restore central vision in patients with age-related macular degeneration, has won European commercial approval and could reach U.S. patient
FDA Approves First Oral PCSK9 Inhibitor Enlicitide
The FDA last week approved Merck's enlicitide (branded Lipfendra) as the first oral PCSK9 inhibitor for lowering blood cholesterol, a milestone that arrives alongside newly aggressive cholesterol guid
MauiWES Becomes Rural Health Hub as Funding Runs Out
The Maui Wildfire Exposure Study, tracking roughly 2,000 Lāhainā fire survivors, has unexpectedly become a de facto rural health hub — and its researchers are racing to spin it out as a nonprofit befo
STAT+: Federal health quality research grants worth $109 million ended early
The federal Agency for Healthcare Research and Quality sent termination notices to dozens of researchers, abruptly ending ongoing health services research grants that had $109.2 million in remaining f
Mars Once Hid Vast Magma Rivers, Oxford Study Finds
Researchers at Oxford analyzing NASA InSight Lander seismic data have found evidence that Mars once had rivers of molten rock pooling 15 miles beneath its surface and stretching hundreds to thousands
Single psilocybin dose leaves brain changes for a month
UCSF and Imperial College London researchers found that a single high dose of psilocybin produced measurable brain activity and structural changes lasting up to a month, linking the psychedelic experi
STAT+: More workers hate their jobs, but keep them for the health insurance
Nearly a quarter of U.S. workers say they want to leave their current job but stay because they can't afford to lose employer-provided health insurance — up sharply from 16% in 2021.
GunaiKurnai cave rituals traced back 25,000 years
Archaeologists at Cloggs Cave in southeastern Australia have uncovered phytolith evidence that GunaiKurnai people conducted grass-burning rituals there for 25,000 years, linking the practice to ceremo
Coffee may protect your heart but energy drinks could harm it
The AHA's new scientific statement finds up to 400mg of caffeine daily — roughly 3-5 cups of black coffee — is generally safe and may protect the heart, while concentrated energy drinks and shots are
UK Evacuates Ebola-Exposed Aid Worker to London Hospital
A UK-resident humanitarian worker with potential healthcare-related Ebola exposure was medically evacuated from DR Congo to a London hospital for precautionary monitoring, with UKHSA confirming the in
Samarkand's Lesson for Silicon Valley: People, Not Silk
An essay drawing on the ancient Silk Road hub of Samarkand argues that the city's prosperity came from welcoming foreign artisans and their knowledge, not just trade goods — a lesson for Silicon Valle
Milky Way flipped in collision with dwarf galaxy 10bn years ago, astronomers say
Durham University astronomers say supercomputer simulations show the Milky Way's disc was flipped more than 90 degrees after a head-on collision with the Gaia Sausage dwarf galaxy roughly 10 billion y
ABC Conjecture Proof Formalization Stuck on 'The Wall'
An interim report from Japan's LANA project shows no progress in using computer formalization to verify Shinichi Mochizuki's controversial 2012 proof of the ABC conjecture, with members citing an unre
STAT+: Pharmalittle: We’re reading about Novo suing Lilly over ‘deceptive’ ads, a fugitive’s secret life in biotech, and more
Novo Nordisk has sued Eli Lilly in federal court, accusing its rival of running a 'deceptive' national ad campaign that unfairly compares competing GLP-1 obesity and diabetes drugs to gain a market ed
Hawley seeks criminal probe of abortion pill makers
Acting Attorney General Todd Blanche committed to halting mail shipments of abortion medication, and Sen. Josh Hawley (R-Mo.) followed by referring the nonprofit Plan C and manufacturer Danco Laborato
Scientists found mystery bacteria inside one of the ocean’s most elusive whales
Florida Atlantic University researchers have identified three previously unknown Helicobacter bacterial genotypes in stranded pygmy sperm whales, with all four infected animals showing stomach ulcers,
Scientists map how flu hijacks cells by dissolving paraspeckles
Scientists at EMBL produced the first molecular map of direct protein contacts between influenza A and human proteins inside intact infected cells, revealing the virus dissolves nuclear paraspeckles t
Spermidine boosted COVID vaccines in older adults
A small pilot trial found that spermidine, a compound naturally present in wheat germ, mushrooms, and aged cheese, improved antibody responses to COVID-19 vaccination in older adults whose immune syst
Umeå Antibody Halts Prostate Cancer Spread in Preclinical Study
Researchers at Umeå University created a fully human antibody that halted growth and metastatic spread of aggressive prostate cancer in preclinical studies via a newly identified mechanism that may ca
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