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STAT+: Newer GLP-1s, pushback on research cuts, and a protest
STAT+ launches its first ADA in 30 Seconds newsletter from the American Diabetes Association’s annual conference in New Orleans. Editor Elizabeth Cooney introduces the briefing, highlighting upcoming
Launch HN: General Instinct (YC P26) – Frontier models on edge devices
General Instinct, a robotics‑focused startup, open‑sourced its InstinctRazor toolkit and demonstrated that the 245 GB BF16 MoE model Qwen3.5‑122B‑A10B can be compressed to a 48 GiB GGUF while preservi
Cambridge AI Coronavirus Vaccine Passes Human Trial
Scientists at the University of Cambridge and spinout DIOSynVax have completed a Phase I trial of an AI‑designed universal coronavirus vaccine in 39 healthy volunteers. The vaccine was safe, well tole
NASA Calls ISS Crew Back After Roscosmos Pauses Repairs
NASA ordered the four Crew‑12 astronauts to board the docked Crew Dragon spacecraft and don spacesuits after an air leak in the Zvezda module worsened, but later announced the crew could resume normal
Genetic variants cause 10% resistance to Ozempic
A Stanford‑led international study identified genetic variants that render about 10% of people less responsive to GLP‑1 receptor agonists such as Ozempic. Carriers of these variants showed poorer bloo
Japan Team Inserts Rat Chromosome into Mouse Embryos
Japanese researchers at Yamanashi University have inserted a deep‑frozen rat chromosome into mouse embryos, producing chimeric mice and demonstrating a new way to study extinct‑animal genes in living
Marty Makary’s FDA Voucher Program Faces Overhaul
RevMed’s experimental pancreatic cancer drug daraxonrasib is being offered via an expanded access program, though patients still face hurdles obtaining it. Meanwhile, the FDA’s voucher program, launch
FDA Reviews Drug Program, Launches Mifepristone Study
The FDA held a listening session on its fast‑track drug review program, hearing from 17 stakeholders and receiving calls to pause the scheme and return to standard procedures. At the same time, the ag
Feyi-Waboso in race to face Boks after facial surgery
England winger Immanuel Feyi‑Waboso had facial surgery after a jaw injury in Exeter’s win over Leicester, ruling him out of the club’s final Premiership match against Saracens. The game, a playoff‑dec
Collatz Conjecture Stumps Math for 90 Years
The Collatz conjecture, a deceptively simple number rule proposed by Lothar Collatz in the 1930s, has stumped mathematicians for nearly a century, with the strongest progress coming from Terence Tao i
US Doctor’s Child Injured by Phenytoin in Scotland
An American pediatric emergency physician recounts how her 11‑month‑old daughter, Leela, suffered a severe extravasation injury after receiving phenytoin for a prolonged febrile seizure in a Scottish
Anglia Ruskin study finds collagen boosts skin, joints
The largest meta‑analysis of collagen supplements, led by Anglia Ruskin University, pooled data from 16 systematic reviews, 113 randomized trials and nearly 8,000 participants. It found that regular c
S&P will not change the rules to allow SpaceX into its benchmark index early - Axios
S&P Global has reaffirmed its existing eligibility rules for the S&P 500 index, ruling out any early inclusion for SpaceX. The decision, reported by Axios, Bloomberg, Reuters and the Wall Street Journ
FDA Listens to 17 Critics on Makary’s Voucher Program
During a White Oak Campus listening session, the FDA heard from 17 speakers—including patient groups, drug firms, and academics—who largely urged a pause to the Commissioner’s National Priority Vouche
RevMed's Daraxonrasib Gets Standing Ovation at ASCO
The STAT podcast “The Readout LOUD” highlighted the enthusiastic reception of Revolution Medicines’ pancreatic cancer drug daraxonrasib at the ASCO meeting, featuring patient Leanna Stokes’ personal s
Otsuka's Voyxact Slows Kidney Decline to 3 Points/Year
Otsuka’s Phase 3 trial of its drug Voyxact in patients with IgA nephropathy showed an annualized eGFR decline of 3 points per year, versus 7.6 points for placebo. Although the drug slowed kidney funct
Zoetis, Elanco Stocks Surge After Texas Screwworm Case
A New World screwworm parasite was confirmed in Texas livestock, prompting a market rally for animal‑health firms. Zoetis shares rose nearly 4% and Elanco Animal Health up 2%, while Zoetis options vol
STAT+: Supreme Court backs generic drugmaker in ‘skinny labeling’ case
The U.S. Supreme Court issued a unanimous decision that Hikma Pharmaceuticals does not infringe Amarin's patents, overturning a lower‑court ruling that had favored Amarin. The ruling strengthens gener
Daraxonrasib doubles pancreatic cancer survival
Pancreatic cancer patient Amy Johnston, awaiting trial results, may turn to the experimental drug daraxonrasib if her current treatment fails. Daraxonrasib, developed by Revolution Medicines, nearly d
First Non-Repeating Biological Clock Found in Worms
Cold Spring Harbor Laboratory researchers have identified a two-protein feedback circuit — MYRF-1 and LIN-42 — that acts as the master developmental clock in C. elegans, coordinating precisely timed b
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