College Football Week 1 Top 25 Picks Against the Spread — SkimNews

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- Clemson travels to No. 11 LSU Saturday (7:49 p.m. ET, ABC) in the "Battle of Tigers," pitting Dabo Swinney's portal-averse program against Lane Kiffin's No. 1 transfer class — expert pick: Under 50
- Lane Kiffin is fighting the SEC — which is suing LSU — over his bid to play two former NFL players, adding off-field drama to his Baton Rouge debut
- Oregon vs. Boise State pick goes Under 51.5 (3:30 p.m. ET, CBS), with the Ducks' elite interior defensive line expected to shut down the Broncos' ground game
- Record-breaking heat in the South will test No. 13 Alabama, No. 3 Georgia, and No. 20 Tennessee during Saturday's openers
- Notre Dame vs. Wisconsin pick takes Wisconsin +20.5 (Sunday, 7:30 p.m. ET, NBC), with CJ Carr leading the Irish to a comfortable win but the Badgers covering behind junior QB Colton Joseph Jr.
- Florida State vs. No. 19 SMU pick takes SMU -3 (Monday), with Kevin Jennings expected to exploit a Seminoles secondary that struggled in Week 0
Why it matters: The Clemson-LSU 'Battle of Tigers' doubles as a referendum on roster-building philosophy — Swinney's portal-avoidance against Kiffin's No. 1 transfer class — while Kiffin simultaneously fights the SEC (which is suing LSU) over eligibility for two former NFL players. Both marquee-game totals lean Under (50 and 51.5), signaling expected defensive slugfests.
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