U.S. Funds Ibogaine Trials; AstraZeneca Opens Boston R&D Center — SkimNews

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- The Trump administration is advancing the first government-funded clinical trials of ibogaine to treat opioid addiction and PTSD, following an April executive order that dedicated $50 million to federal ibogaine research.
- The FDA opened a public docket seeking feedback on ibogaine trial design, dose selection, patient eligibility, safety monitoring, study-stopping rules, and oversight, with comments due Nov. 20.
- AstraZeneca opened a new 570,000-square-foot, 18-story R&D center in Cambridge, Mass.'s Kendall Square biotech cluster, the centerpiece of a $1 billion Massachusetts investment program.
- The Cambridge facility sits within AstraZeneca's broader ~$50 billion investment program, first announced in 2024 and "dramatically expanded" last year.
- Veterans and experts have called for strict safety standards on psychedelic treatments as the federally backed ibogaine trial push gains momentum.
Why it matters: AstraZeneca's 570,000-square-foot Kendall Square facility anchors a $1 billion Massachusetts investment within a broader $50 billion program, while the FDA's Nov. 20 ibogaine docket deadline gives researchers, veterans, and drugmakers a narrow window to shape the design of the first federally funded psychedelic trial.
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