49ers' Bosa Out Weeks With Calf Injury — SkimNews
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- Nick Bosa suffered a calf injury in practice that will keep him out for several weeks and rules him out against the Arizona Cardinals, as the 49ers assess whether to place him on injured reserve
- San Francisco 49ers face a deepening defensive line crisis after placing C.J. West on IR and losing Sam Okuayinonu, Alfred Collins, and James Thompson Jr. to season-ending injuries from practice
- Rookie James Thompson Jr. is expected to miss three to six weeks with a high ankle sprain, further depleting the 49ers' interior defensive line depth early in the season
- Romello Height is dealing with a broken hand that has kept him out of practice, though he has an outside chance to play against Arizona according to coach Kyle Shanahan
- Kyle Shanahan acknowledged the complexity of managing only eight return-from-IR designations, forcing the team to strategically decide who gets placed on the list amid mounting injuries
Why it matters: The 49ers lose their top pass rusher at a critical time, compounding a defensive line already stripped of four key players to IR. With limited IR return slots and a thin rotation, San Francisco’s ability to pressure quarterbacks and stop the run becomes materially weaker—just as they prepare for a tough stretch without Bosa, whose absence could reshape their defensive strategy for weeks.
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