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A single protein may be holding back CAR T cancer therapy

By Science Daily · Summarized & edited by · 2026-06-02
A single protein may be holding back CAR T cancer therapy

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A newly identified protein may be one of the biggest obstacles holding CAR T-cell therapy back. Researchers found that NFIL3 causes these engineered immune cells to become exhausted and lose their cancer-fighting power over time. When NFIL3 was disabled, the cells remained stronger for longer and co

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