NFL odds: Week 5 parlays featuring favorites, underdogs include Bears vs. Packers, 49ers vs. Seahawks — SkimNews

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- Mike Tierney (SportsLine) released six Week 5 NFL parlay picks on a 13-game 2026 slate, riding a 320-271-16 track record over four seasons and a 130-101 ATS (56.3%) mark over the past two.
- Cincinnati Bengals anchor the favorites parlay against the Dolphins, whose offense has scored just four touchdowns all season and lost RB De'Von Achane for the year, while the Bengals yield two touchdowns per outing to effective attacks.
- Chicago Bears are a favorites pick over Green Bay on the strength of a 60% time-of-possession rate (36 minutes per game, four more than the next-best team) and 196.3 rushing yards per game, compared to the Packers' league-low 26 minutes and 58 rushing yards per game.
- Atlanta Falcons close the favorites parlay vs. Baltimore after the line moved roughly a touchdown when Lamar Jackson was labeled doubtful, with Bijan Robinson coming off a 145-yard, two-touchdown Monday and Michael Penix Jr. back at QB for Atlanta.
- Cleveland Browns lead the underdogs parlay against the Jets, an unusual plus-money spot for a team on a three-game straight-up win streak, with Deshaun Watson posting a 72% completion rate while New York comes off one of the worst offensive performances Tierney describes as 'one of the sorriest duds in NFL annals.'
- San Francisco 49ers cap the underdogs parlay as a plus-money pick at Seattle, with Brock Purdy in 'MVP form' behind a clean O-line, while the Seahawks face their own injury concerns and a defense that has been 'un-Seattle-like' the past two games.
Why it matters: NFL bettors weighing the Week 5 slate have a substantive data point in Tierney's 320-271-16 record over four seasons and 130-101 ATS (56.3%) mark the past two — and his contrarian calls (Bears as heavy favorites over slumping Green Bay, 49ers catching plus-money against Seattle) flag where value sits on a 13-game board that includes the undefeated Vikings and Lamar-Jackson-doubtful Ravens.
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