NFL Week 2 injury report: Lions down two starting offensive lineman vs. Bills, including Blake Miller — SkimNews

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- Detroit Lions ruled out starting OT Blake Miller (knee) and OG Christian Mahogany (hip) for Thursday Night Football vs the Bills, with CB D.J. Reed listed as questionable after limited practice Tuesday and Wednesday
- Buffalo Bills list S Cole Bishop (knee/groin), RB Ty Johnson (hamstring) and DL T.J. Sanders (knee/illness) as questionable, with all three limited at Wednesday's practice
- Sam Darnold (Seahawks QB) remained out of practice Wednesday with a glute injury and is expected to miss roughly four weeks, though the team will not place him on injured reserve
- Kyler Murray (Vikings QB) was a limited Wednesday participant after suffering a concussion in the first quarter of his Vikings debut in Week 1
- Joe Burrow (Bengals QB) was limited Wednesday with a back injury but told reporters he plans to play Sunday against the Texans; pass rusher Shemar Stewart was a full participant with his knee issue
- Cedric Gray (Titans LB) cleared concussion protocol after missing the Week 1 opener vs. Chicago and was a full participant in Wednesday's practice, with LB James Williams limited by an elbow injury
- Week 1 fallout — Patriots WR A.J. Brown (ankle), Eagles LG Landon Dickerson (knee) and Rams pass rusher Myles Garrett (knee) all landed on injured reserve following opening weekend
Why it matters: Detroit's offensive line depth faces its first test on a short TNF week against a Bills defense that, despite three questionables of its own, will test a reshuffled Lions front. Across the league, Burrow playing through a back injury keeps Cincinnati's offense intact for Sunday, while Seattle absorbing a four-week Darnold absence without using IR preserves roster flexibility for the stretch run.
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