Collins, Flowers Ruled Out; Burrow, Nacua Questionable — SkimNews

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- Nico Collins (WR, Texans) is ruled out for Week 2 with a hamstring injury, funneling extra volume to Kayshon Boutte and tight end Dalton Schultz.
- Zay Flowers (WR, Ravens) is officially out after exiting Week 1 with a hamstring injury, making Rashod Bateman Baltimore's No. 1 receiver and elevating Mark Andrews as a TE1.
- Joe Burrow (QB, Bengals) is listed as questionable with back soreness but will start against the Texans, calling it "ridiculous" for the injury to sideline him.
- Puka Nacua (WR, Rams) is questionable with a hip injury and likely a game-time decision for Monday night against the Giants.
- A.J. Brown (WR, Patriots) was placed on IR with a high-ankle sprain and could miss up to six weeks, with a ramp-up period expected when he returns.
- Brock Bowers (TE, Raiders) is doubtful to play Week 2 after meniscus surgery; Michael Mayer, who drew a team-high seven targets in Week 1, is the primary fill-in.
- Three quarterbacks are out: Kyler Murray (concussion), Sam Darnold (glute), and Michael Penix Jr. (knee) are all ruled out, while Jordan Mason (RB, Vikings) hits IR with a fractured thumb for at least four games.
Why it matters: Fantasy managers face cascading Week 2 lineup decisions: A.J. Brown's six-week IR stint and Jordan Mason's four-game minimum absence force long-term roster pivots, while Monday-night uncertainty on Nacua forces holding a backup through kickoff. Multiple backup QBs — including Carson Wentz — suddenly become top streaming options.
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