NFL Power Rankings: 1-32 poll, plus the biggest offensive issue for each team — SkimNews

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- San Francisco 49ers remain No. 1 at 6-0 but are battling a wide receiver injury crisis, with Ricky Pearsall, De'Zhaun Stribling, Christian Kirk and Demarcus Robinson all landing on IR before Week 3, plus Deebo Samuel Sr. out with a hamstring injury
- Los Angeles Rams fell out of the top 10 for the first time this season after their second straight loss, becoming just the fifth team in 50 seasons to enter a year as the outright Super Bowl favorite and lose at least four of their first six games
- NFC East teams made NFL history by becoming the first division to be winless in consecutive weeks in which every team played, with the Cowboys dropping six spots, Eagles five and Giants four in the rankings
- Houston Texans are climbing the rankings after rebounding from an 0-4 start with two straight divisional wins, including the London debut of Marvin Harrison Jr. (3 receptions, 34 yards) after his trade from the Cardinals
- Kansas City Chiefs (5-0) are managing a worsening offensive tackle situation, with left tackle Josh Simmons (bulging disk) still out and right tackle Jaylon Moore exiting with a concussion against the Chargers
- Seattle Seahawks lead the NFL's turnover problem at 12 giveaways (third most), with Sam Darnold throwing seven interceptions in four games since returning from a glute injury and 44 points scored off Seattle's turnovers in three losses
- Denver Broncos' Bo Nix is mired in a sophomore slump, ranking near last in nearly every metric, which coach Sean Payton attributed to 'a lot of dirty hands' as the defense keeps bailing out the offense
Why it matters: The Week 6 rankings underscore an injury-driven offensive crisis league-wide — the 6-0 49ers are leaning on a gutted wide receiver room while a historically favored Rams squad has dropped out of the top 10. Fantasy managers and bettors tracking the 49ers' remaining schedule now have to weigh whether 6-0 reflects sustainable production or papered-over attrition.
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