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College football picks: Predictions against the spread, odds, betting lines for top 25 games in Week 4 — SkimNews

By CBS Sports · Summarized & edited by · 2026-09-25
College football picks: Predictions against the spread, odds, betting lines for top 25 games in Week 4

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Why it matters: Six ranked matchups on one Saturday — the most in three years — arrive just as College Football Playoff contenders face do-or-die conference tests; per the article's data, a 0-2 conference start has historically eliminated every team from the 12-team playoff, meaning Saturday's losers aren't just behind — they're functionally out. Bettors and fans get rare scheduling density, but Texas A&M and LSU essentially play a September elimination game.

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