Revolution Daraxonrasib Doubles Pancreatic Survival

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- Revolution Medicines announced a Phase 3 trial where daraxonrasib extended median survival to 13.2 months, versus 6.7 months on standard chemotherapy (per company statement).
- Daraxonrasib is a daily oral pill that showed a striking survival benefit in advanced pancreatic adenocarcinoma (per trial data).
- Paul Oberstein of NYU Langone’s Perlmutter Cancer Center, a trial investigator, highlighted the result as a potential “new era” for pancreatic cancer treatment (per STAT interview).
- FDA could approve the drug quickly once Revolution submits the data, potentially delivering the first approved oral therapy for this disease (per company comment).
Why it matters: Patients with advanced pancreatic cancer could receive an FDA‑approved oral therapy within months, offering a new treatment option.
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