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Foot‑Angle Gait Training Cuts OA Pain, Slows Damage
A year‑long randomized trial led by the University of Utah, NYU and Stanford shows that a small, personalized foot‑angle change while walking can relieve knee osteoarthritis pain as effectively as med
SpaceX spends $131M Cybertrucks promises $1B Mars award
SpaceX filed a 300‑page prospectus for its $1.75 trn IPO, disclosing $131 m spent on Cybertrucks, a $1 bn share award for a 1 m‑person Mars colony, AI‑Grok risk warnings, $4 m in Musk security costs a
How ageing on Earth mimics the effects of space travel
NASA’s twin study reveals that long‑duration spaceflight dramatically accelerates biological aging, with a six‑month mission aging an astronaut 40× faster than a twin on Earth. Astronaut Scott Kelly’s
STAT+: Genentech is soliciting research that can be used to blunt pharma reforms in Washington
While headlines have focused on a tight U.S. energy market, Genentech is now turning its attention to the policy arena, offering up to $125,000 grants to generate research that can shape the debate ov
Study Finds GLP‑1 Drugs May Ease Arthritis Inflammation
After covering the NFL’s 2026 international schedule, SKIMNEWS now turns to a medical breakthrough: Aarhus University researchers show that high‑dose GLP‑1 drugs, best known for weight loss, may direc
Review: Senescent Cells Help Healing, Spur Anti‑Aging
A new review reveals that not all senescent “zombie” cells are detrimental; some play vital roles in healing and tissue balance. This nuanced view is driving a push for precision anti‑aging treatments
Aging‑US Review Links Early Damage to Cancer Arthritis
Scientists from University College London and Queen Mary University of London propose a two‑stage aging model in which hidden damage from early life—such as infections, injuries, or genetic mutations—
STAT+: Closely watched experimental Parkinson’s drug fails key clinical trial
Biogen and Denali Therapeutics’ LRRK2‑targeting drug flopped in a 648‑patient trial, failing to slow Parkinson’s progression. The result deals a blow to the hypothesis that blocking LRRK2 could benefi
UK Melanoma Cases Hit Record 20,980 in 2022
Cancer Research UK analysis shows melanoma cases in the UK have hit a record high of nearly 21,000 diagnoses in 2022, with the charity projecting more than 26,500 new cases annually by 2040.
Sacituzumab tirumotecan Cuts Tumor Progression 65%
A Phase 3 trial in China shows that Merck‑licensed, Kelun‑Biotech’s antibody‑drug conjugate sacituzumab tirumotecan slashes tumor progression by 65% in untreated advanced non‑small‑cell lung cancer, m
The Readout LOUD Flags AI Longevity, Chinese Biotech
In a recent episode of The Readout LOUD, hosts unpacked the biotech landscape from the STAT Breakthrough Summit West, spotlighting BridgeBio’s own concerns about research rigor, Retro Biosciences’ AI‑
Early junk‑food diet rewires brain; probiotic helps
A University College Cork study shows that high‑fat, high‑sugar diets in early life permanently alter brain appetite circuits in mice, yet probiotic and prebiotic treatments can partially restore heal
STAT+: Pharmalittle: We’re reading about a Lilly obesity drug trial, statistics for an Alzheimer’s drug, and more
Eli Lilly’s next‑generation obesity pill delivered weight loss rivaling bariatric surgery—28 % on average—but an 11 % adverse‑event dropout rate exceeds the 7 % seen with competitors, casting doubt on
US Ebola Quarantine Policy May Deter Volunteers, Critics Warn
The US is refusing to evacuate an American Ebola patient and six virus-exposed citizens home, instead routing them to Germany and the Czech Republic, while also mandating that hantavirus-exposed cruis
GLP‑1 drugs cut heart attacks and strokes by 13%
A comprehensive meta‑analysis of 11 cardiovascular outcome trials shows that GLP‑1 receptor agonists significantly cut major heart events, strokes and premature deaths by roughly 13% in over 90,000 hi
Chlorpyrifos Exposure Linked to Child Brain Damage
Prenatal exposure to the pesticide chlorpyrifos is linked to lasting brain structural, functional, and metabolic changes and reduced motor performance in children, according to a new JAMA Neurology st
Women’s better memories may delay Alzheimer’s diagnosis by years
A new study shows that women’s stronger verbal memory can conceal early Alzheimer’s pathology, letting them score normally on standard tests for nearly three years longer than men. This hidden reserve
PerturbFate Finds Shared Hubs Across Cancer Mutations
Scientists at Rockefeller University unveiled PerturbFate, a single‑cell tracking platform that maps how hundreds of cancer‑linked mutations converge on common regulatory hubs. By testing the system o
STAT+: Lilly’s ‘triple-G’ drug leads to bariatric-surgery levels of weight loss in trial
Eli Lilly’s experimental obesity drug retatrutide delivered an average 28.3% weight loss in a Phase 3 trial, approaching the results of bariatric surgery. However, 11% of participants on the highest d
Surgeon General Issues Screen‑Time Warning for Kids
The U.S. Surgeon General’s Office, under Health Secretary Robert F. Kennedy Jr., released a draft advisory urging a sharp cut to children’s screen time, echoing earlier Biden‑era concerns. The report
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