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Vinay Prasad exits FDA, therapy firms get approvals
Gene therapy leaders at a Rome conference pointed to recent FDA approvals for rare‑disease drugs from Rocket and Regeneron as a bright spot, but the abrupt departure of Vinay Prasad, the FDA’s top gen
NHS Trials Double Cochlear Implants for Deaf Adults
A 72-year-old retired opera singer who hid her deafness for three decades is backing a nationwide NHS trial of bilateral cochlear implants that could overturn NICE guidelines currently restricting mos
Colon cancer breakthrough keeps patients cancer-free for nearly 3 years
A brief pre‑surgery course of pembrolizumab has halted cancer recurrence for nearly three years in high‑risk stage 2/3 colorectal patients, overturning the traditional surgery‑then‑chemo paradigm. The
Partial meniscectomy ineffective, worsens knee health
A decade‑long Finnish trial shows that partial meniscectomy, one of the world’s most common knee surgeries, provides no benefit over sham procedures. Moreover, patients who received the operation expe
Inconsistent Bedtimes Double Heart Attack Risk: Study
A decade-long study of 3,231 Finnish adults found that highly inconsistent bedtimes at age 46 roughly doubled the risk of major cardiovascular events, especially among those sleeping under eight hours
FDA blocks COVID‑19 and shingles vaccine safety papers
An HHS spokesperson says the FDA pulled three large‑scale safety studies on COVID‑19 and shingles vaccines after the authors were judged to have over‑reached their data, despite the papers being accep
STAT+ Teases AI Diagnosis Debate at Summit West
STAT+ teases a deep dive into AI diagnostic performance, but the article is mainly a subscription plug and a preview of an interview with OpenEvidence CTO Zachary Ziegler at the upcoming Breakthrough
GLP-1 Users Face More Judgment Than Non-Losers: Study
A Rice University study finds that people who lose weight using GLP-1 drugs like Ozempic and Wegovy are judged more harshly than those who lose weight through diet and exercise—or even those who never
Patient Groups Rate Pharma 57% Good, Pricing Concerns
A new PatientView survey of 2,400 patient groups across 35 countries finds that 57% now rate drugmakers as excellent or good – a modest rise from 56% last year but still below the 60% peak in 2022. Th
NHS to hide open-source code by May 11 AI hack risk
NHS England will hide its taxpayer‑funded open‑source software by May 11, citing AI‑driven hacking risks from Anthropic’s Mythos, sparking backlash from experts, an open letter and concerns over secur
Psilocybin Dose Triggers Brain Structure Changes
A single 25 mg dose of psilocybin reshaped brain structure in healthy volunteers, with diffusion MRI showing denser front‑to‑midbrain tracts a month later. The change coincided with heightened EEG ent
Vertex Shelves mRNA Drug; Cytokinetics Hits Efficacy
Biotech earnings and trial updates show mixed progress: Vertex Pharma's Q1 results matched expectations but it shelved its mRNA cystic fibrosis candidate VX‑522 after tolerability concerns; Viridian T
WHO Pandemic Treaty Stalled Nations Miss Pabs Deadline
World leaders missed a key deadline to lock in a pathogen‑access and benefit‑sharing framework, leaving the newly‑adopted pandemic treaty stalled. Rich nations and low‑income blocs clash over whether
Cytokinetics' Myqorzo Hits Dual Endpoints in HCM Trial
Cytokinetics announced that its heart‑failure drug Myqorzo achieved both primary efficacy endpoints in the Phase 3 ACACIA trial for non‑obstructive hypertrophic cardiomyopathy, delivering statisticall
UK charity says Alzheimer’s diagnoses block trials
UK patients are being left behind as a surge in Alzheimer’s drug trials—spurred by modestly effective anti‑amyloid medicines like lecanemab and donanemab—outpaces early, accurate diagnoses. Alzheimer’
Leah Crane flags shaky physics of inflation models
Leah Crane warns that inflationary cosmology’s physics remains unsettled, highlighting fine‑tuning concerns and recent quadratic‑gravity work that may tame problematic ghost particles while predicting
Early Eating Cuts Weight, Improves Metabolism
A new meta‑analysis of 41 trials finds that eating earlier in the day, even without cutting calories, yields weight loss and metabolic health gains across 2,200 adults aged 19‑69, with improvements in
Doug Whitney's Heat Exposure Lowers Alzheimer Risk
A U.S. mechanic with a deadly Presenilin‑2 mutation has avoided early‑onset Alzheimer’s, possibly thanks to chronic heat exposure in ship engine rooms. Researchers link his high heat‑shock‑protein lev
Travel May Slow Aging, ECU Study Says
A 2024 Edith Cowan University study proposes that positive travel experiences may slow aging by supporting the body’s resilience and balance through novelty, activity, and social connection, while war
Honey has been used as medicine for centuries – does it really work?
Honey’s health reputation hinges on its source: some varieties like Sidr tree honey have a low glycemic index (32) and antioxidant‑rich phenolics, while others such as Greek thyme honey spike blood su
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