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Polyamines fuel cancer via eIF5A2, Tokyo study finds
A Tokyo University study reveals how polyamines fuel cancer growth by activating a specific protein pathway, resolving a long-standing puzzle about their dual role in aging and tumor progression.
SNAC in Ozempic and Wegovy pills linked to gut changes
Adelaide University researchers, in the first systematic in vivo study of repeated SNAC exposure, found the oral semaglutide absorption enhancer was associated in animals with depleted beneficial gut
Arts Boost Brain Health and Reduce Disease Risk
A growing body of research shows that regular participation in the arts triggers physiological changes that improve brain health, lower stress and inflammation, and reduce risk of depression, chronic
Cigna Acquires CarepathRx, Serving 10% of U.S. Hospitals
Cigna’s purchase of CarepathRx, a pharmacy serving roughly a tenth of U.S. hospitals, marks a strategic push to deepen its control over prescription drug distribution and intensify its vertical integr
New IBD treatment offers hope for 70% of patients
A new treatment approach offers hope for the 70% of inflammatory bowel disease (IBD) patients who don't find relief from existing medications, potentially transforming the treatment of Crohn's disease
Vaccines Reduce Heart, Stroke and Dementia Risks Up to 34%
Multiple studies reveal that vaccines—including shingles, flu, RSV, COVID‑19, and measles shots—significantly lower the risk of heart disease, stroke, and dementia, highlighting far‑reaching health be
Waterloo Engineers Tumor-Eating Bacteria With Safety Switch
University of Waterloo researchers are engineering Clostridium sporogenes bacteria to invade solid tumors and consume them from the inside, using a quorum-sensing switch to keep an added oxygen-tolera
UCLA blocks NDRG1 to speed muscle repair in aged mice
UCLA researchers discovered that inhibiting the protein NDRG1 in aged mice restores rapid muscle repair, revealing a survival‑versus‑function trade‑off that underlies age‑related stem‑cell slowdown an
Mount Sinai Study Finds 42 PFAS in Newborn Cord Blood
A Mount Sinai study using non‑targeted analysis of umbilical cord blood from 120 infants (2003‑2006) uncovered 42 PFAS compounds, showing prenatal exposure is far broader than previously recognized an
St. Francis's Skeleton Goes on Public Display in Assisi
The skeleton of Saint Francis of Assisi went on full public display in Italy for the first time, drawing nearly 400,000 reservations from around the world for a month-long viewing in the basilica buil
Polygenic embryo selection outpaces US regulation
Stanford bioethicist Daphne O. Martschenko and Princeton sociologist Sam Trejo argue in their new book that polygenic embryo screening is advancing with almost no US oversight, even as the underlying
UCL Trial Reveals Body's Inflammation Off Switch
UCL researchers identified epoxy-oxylipins — fat-derived molecules that act as the body's natural off switch for inflammation — and showed that boosting them with an existing drug accelerated pain res
STAT+: Pharmalittle: We’re reading about China’s homegrown GLP-1 drugs, a puzzling FDA rejection, and more
Eli Lilly is investing $1 billion to transform India into a global supply chain hub, capitalizing on the booming demand for weight-loss drugs like its top-selling medicine in a country projected to ha
CRISPR Sensor Detects Lung Biomarkers at Sub‑Attomolar
A Shenzhen University team has unveiled a CRISPR‑powered, amplification‑free light sensor that detects lung‑cancer biomarkers in blood at sub‑attomolar concentrations, a capability that supports routi
Lawmakers Consider Ban on Drug Ads to Consumers
Lawmakers are considering banning pharmaceutical companies from advertising directly to consumers, spurred by concerns that the elderly are particularly vulnerable to industry targeting. This renewed
Single DMT dose eases treatment-resistant depression in trial
A 34-person trial found a single dose of DMT combined with psychotherapy produced rapid, lasting relief in treatment-resistant depression, with benefits persisting three to six months after one sessio
UVA Finds Caspase‑8 Kills Toxoplasma‑Infected T Cells
UVA researchers found that the brain parasite Toxoplasma gondii infects CD8+ T cells, but the cells’ caspase‑8–driven self‑destruction eliminates the parasite, explaining why one‑third of people carry
Dana‑Farber Cuts Brigham Tie, Staff Feel ‘Divorce’
Dana‑Farber’s 2023 decision to end its partnership with Brigham and Women’s Hospital and partner with Beth Israel Deaconess is causing staff discomfort and a messy unwind as the contract runs to 2028
Dawei Lu team reverses heat flow in quantum qubits
Researchers led by Dawei Lu at Southern University of Science and Technology have demonstrated that quantum coherence can drive heat from a colder qubit to a hotter one, effectively reversing the usua
Kent couple, married 44 years, both diagnosed with kidney cancer
A Kent couple married for 44 years were both diagnosed with kidney cancer two years apart, with neither showing symptoms before the tumours were discovered during treatment for other cancers.
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