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TDP43 Controls DNA Mismatch Repair, Ties ALS & Cancer
Researchers discovered that TDP43, a protein known for ALS and dementia, also regulates DNA mismatch repair, linking neurodegeneration to cancer and pointing to potential treatment strategies that mod
Durham finds stable proteins that boost LAMP speed
Durham University led a team that uncovered DNA‑binding proteins from Icelandic volcanic lakes and North Atlantic vents, whose thermal and chemical stability boosted speed and sensitivity of LAMP test
China's quantum dot yields 98.3% entangled photon pairs
Researchers at the Beijing Academy of Quantum Information Sciences have engineered quantum dots to emit entangled photon pairs on demand with a 98.3% pair‑generation efficiency, a breakthrough that co
UCSF Study Finds Surface Src Kinase on Tumor Cells
UCSF biologist Jim Wells discovered the Src kinase, normally intracellular, present on the surface of malignant cells but not healthy tissue, a finding that could open new avenues for solid‑tumor immu
Epstein associate raises $100M for biotech comeback
A STAT biotech podcast episode reveals that a Jeffrey Epstein associate secured a $100 million fundraising round for a biotech comeback with a top VC, and probes whether Vinay Prasad will make a three
Telehealth prescribers face FDA scrutiny over
Medical groups affiliated with telehealth companies the FDA warned about marketing of compounded weight loss drugs may b...
Podcast ties exercise, hedgehog hearing, AI bias
In a new Guardian science podcast, editor Ian Sample and guest Madeleine Finlay discuss three recent studies linking exercise to brain health, revealing hedgehogs’ ability to hear ultrasound, and expo
BioNTech Founders Launch mRNA Firm; Senator Probes FDA
BioNTech’s co‑founders are exiting to launch a new mRNA venture while a Wisconsin senator demands the FDA release its rare‑disease denial letters, highlighting both biotech reshuffling and regulatory
AI Labels Cut True Info Trust, Boost False Claims: Study
A new JCOM study finds that AI disclosure labels paradoxically reduce the perceived credibility of true scientific information while increasing the credibility of false claims — the opposite of what t
165K-Patient Study: No Safe Group for Risperidone
A study of over 165,000 UK dementia patients found the antipsychotic risperidone raises stroke risk across all patient groups—including those with no prior cardiovascular disease—contradicting the bel
Purdue sperm-protein vaccine cuts animal fertility 67%
Purdue University researchers developed a contraceptive vaccine targeting the IZUMO1 sperm protein that cut animal fertility by 59–67% in trials, with a three-year horse study now in its first year.
4e reduces psychedelic behavior in mice
Researchers have synthesized a fluorinated psilocin derivative, 4e, that delivers stable brain exposure and activates serotonin receptors while producing far fewer psychedelic-like behaviors in mice,
Mayo Clinic IDs MET Gene Mutation Causing Fatty Liver
Mayo Clinic researchers have identified a rare inherited mutation in the MET gene that can directly cause metabolic dysfunction-associated steatotic liver disease, a condition affecting roughly one-th
Hebrew University finds nitric oxide autism link
Researchers at the Hebrew University of Jerusalem identified a nitric‑oxide‑driven molecular cascade that disables the TSC2 brake and over‑activates mTOR, offering a new mechanistic link to autism and
Cambridge Study Links Retriever Genes to Human Anxiety
A Cambridge study of 1,300 golden retrievers finds that several genes shaping dog temperament also influence human anxiety, depression, and intelligence, highlighting shared genetic roots for emotion
Plant Mitochondria Pull Oxygen from Chloroplasts
A University of Helsinki study shows that plant mitochondria actively consume oxygen produced by chloroplasts, revealing a direct intracellular oxygen exchange that influences photosynthesis and stres
CAS scientists build first model to map global salt marsh carbon
Scientists at the Chinese Academy of Sciences have built SAL-GPP, the first process-based model designed specifically for salt marsh ecosystems, enabling the most accurate global accounting yet of blu
Scientists boost MeCP2-E1 by skipping e2 in Rett study
Scientists demonstrated that removing a specific gene segment can increase the MeCP2‑E1 protein in mouse models and patient‑derived cells, offering a promising preclinical approach for treating Rett s
Prime Medicine asks FDA for 2‑patient prime‑editing
Prime Medicine announced it will request FDA approval for a gene‑editing therapy that has only been administered to two patients, marking the first use of prime editing to treat chronic granulomatous
Young Cancer Survivors Age Faster at Cellular, Brain Level
Young cancer survivors show signs of faster biological aging at both cellular and brain levels, with chemotherapy accelerating the process most dramatically, according to a study of roughly 1,400 long
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