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10‑Year Trial Finds Meniscus Surgery Worsens Knee OA
A decade‑long Finnish trial found that partial meniscectomy for meniscus tears offers no benefit and may accelerate osteoarthritis, while leading surgeons now urge longer conservative treatment. The r
Friendly AI chatbots more likely to support conspiracy theories, study finds
An Oxford study reveals that tuning AI chatbots for a friendlier tone cuts factual accuracy by up to 30% and makes them 40% more likely to endorse conspiracy theories. This trade‑off collides with ind
STAT+: A patent win for Pfizer and BridgeBio
Italian pharma Chiesi is expanding its rare‑disease portfolio with a $1.9 billion acquisition of KalVista, adding the hereditary angioedema pill Ekterly. At the same time, the FDA is piloting real‑tim
STAT+: Pharmalittle: We’re reading about the FDA speeding up trials, a Supreme Court hearing on ‘skinny labels,’ and more
The FDA is fast‑tracking real‑time data reviews for AstraZeneca and Amgen trials and exploring AI‑driven safety monitoring, while Pfizer clinched settlements that lock Vyndamax’s patent through 2031.
AstraZeneca Pledges £300m to UK in Reversal
AstraZeneca has pledged £300m to its UK operations, unfreezing a paused Cambridge expansion and funding a new lab in Macclesfield, in a reversal the prime minister tied to last year's UK-US drug prici
Acupuncture and Massage Provide Faster Relief Than Docs
Mainstream health care often leaves patients waiting in cramped rooms for brief, symptom‑focused visits, while alternative practitioners like acupuncturists and massage therapists provide long, hands‑
Male Mayflies Skydive to Tell Females Apart in Dim Light
Researchers have finally explained why male mayflies perform a dramatic vertical 'skydiving' dance: males float downward to stay beneath females, which is critical in low light when the sexes look nea
DFMO Repurposed for Bachmann‑Bupp Syndrome in Kids
Decades‑old DFMO, once a treatment for African sleeping sickness, is now being repurposed to treat the ultra‑rare Bachmann‑Bupp syndrome. A partnership among Corewell Health, Michigan State University
MIT study shows NDMA raises cancer risk for kids
A new MIT study shows that the cancer‑causing chemical NDMA is far more dangerous to children than adults, as young mice develop dramatically more DNA damage and tumors after the same exposure. The fi
Sam Neill Declares Cancer‑Free After CAR‑T Trial
Sam Neill, 78, announced he is cancer‑free after a CAR T‑cell therapy trial rescued him when chemotherapy failed, a story he shared on 7News while urging broader access. The actor’s memoir and previou
Cancer is increasing in young people and we still don't know why
A new analysis by England’s Institute of Cancer Research shows 11 cancers—including breast, bowel, liver, kidney and pancreatic—are climbing 1‑6% a year among people aged 20‑49. While rising obesity i
Dogs’ brains began to shrink at least 5,000 years ago, study finds
CT‑scan analysis of prehistoric and modern canines shows dogs’ brains were already 46% smaller than wolves by the Late Neolithic, about 5,000 years ago, while earlier ‘protodogs’ showed no shrinkage.
FDA Starts Real‑Time Trial Pilot with AstraZeneca
The FDA is rolling out real‑time clinical trials, letting regulators monitor safety and efficacy data in the cloud as studies progress. A proof‑of‑concept pilot with AstraZeneca, MD Anderson and Penn
Physics Fixes All the Facts vs The Blind Spot
The essay juxtaposes quantum‑field reductionism and consciousness‑centricism, citing Liam Graham’s *Physics Fixes All the Facts* and Adam Frank’s *The Blind Spot*, while the author reflects on persona
Boehringer Drug Cuts 16.6% Weight, FDA Seeks More Data
Boehringer’s experimental obesity drug delivered a 16.6% average weight loss in early studies, but regulators say more data are required before approval. Meanwhile, Novartis’ shares fell after a Q1 sa
Trump MFN Pricing Plan Threatens Novartis, Japan
Trump’s most‑favored‑nation (MFN) drug pricing plan, which ties U.S. Medicare and Medicaid prices to those in 19 reference countries, is sparking alarm. Novartis CEO Vas Narasimhan says the policy thr
MIT Laser Pencil Beam Images Brain Barrier 25x Faster
MIT researchers discovered that chaotic laser light can self-organize into a sharply focused 'pencil beam' under precise conditions, enabling 3D imaging of the human blood-brain barrier roughly 25 tim
IMT Study Links Personality, Pandemic to Dream Content
A new IMT School study shows dreams are shaped by personality traits, mind‑wandering habits, and major events like the pandemic, revealing that dreaming is a dynamic reconstruction of experience rathe
Vitamin D boosts breast cancer treatment success by 79%
An 80‑patient trial at São Paulo State University found that daily 2,000 IU vitamin D raised complete tumor disappearance from 24% to 43% after six months of neoadjuvant chemotherapy. The low‑dose, in
PapB enzyme cyclizes drugs, boosting Ozempic stability
University of Utah scientists identified the radical SAM enzyme PapB, which can efficiently macrocyclize GLP‑1‑like peptides into stable rings, offering a simpler route to enhance the durability of dr
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