Michigan vs. Oklahoma prediction, odds, time: 2026 Week 2 college football picks by expert on 15-7 run — SkimNews

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- 11th-ranked Oklahoma faces Michigan at noon ET Saturday at Michigan Stadium in Ann Arbor, with Oklahoma installed as 4.5-point favorites and the over/under set at 43.5.
- Oklahoma enters at 1-0 after a 51-0 rout of UTEP, while Michigan escaped Western Michigan 13-12 on a controversial Hail Mary — a finish that masked 59:59 of being 'thoroughly outplayed,' per Tierney.
- Mike Tierney is picking Under 43.5 total points (-110), arguing Michigan's 'all-but-invisible offense' against Western Michigan and Oklahoma injury concerns will keep both defenses in control.
- Tierney said Michigan QB Bryce Underwood 'might have removed himself from Heisman Trophy consideration before Labor Day,' a striking critique after a Week 1 win.
- Oklahoma leads the all-time series 2-0, including a 24-13 win in Norman last season; Oklahoma finished 6-2 in SEC play (10-3 overall) while Michigan went 7-2 in the Big Ten (9-4 overall) in 2025.
- Tierney is 121-103 on college football betting over the past two seasons and 15-7 (+718 units) on his last 22 picks involving Michigan games.
Why it matters: Tierney's Under call carries weight given his 15-7 (+718) record on his last 22 Michigan-specific picks, and the 43.5 total reflects genuine skepticism about two ranked programs' offenses after Week 1 — Oklahoma's 51-0 win against UTEP offers no real evidence, while Michigan mustered just 13 points and a Hail Mary against Western Michigan, raising real questions about QB Bryce Underwood's ceiling.
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