Prisco's Week 1 NFL Picks: Seahawks Top Patriots Rematch — SkimNews
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- Pete Prisco picked the Seattle Seahawks to beat the New England Patriots 26-14 in the Wednesday night opener, calling it a rematch of February's Super Bowl that will play out like the original.
- Prisco picked the Buffalo Bills to snap a six-game losing streak in Houston, predicting a 23-20 win over the Texans by attacking C.J. Stroud into turnovers.
- Patrick Mahomes makes his first start since tearing his ACL in the Monday night finale, with Prisco picking the Chiefs to beat the Broncos 20-17 at home.
- Aaron Rodgers starts what Prisco called 'his final season' at quarterback for the Pittsburgh Steelers, whom he picked to beat the Falcons 27-17.
- Prisco picked the Los Angeles Rams to edge the San Francisco 49ers 28-27 in Thursday's game airing on Netflix from Australia.
- Mike McDaniel's new-look Chargers offense is picked to demolish the Arizona Cardinals 31-14, with Prisco expecting a run-heavy attack and big play-action shots from Justin Herbert.
- Prisco picked the Dallas Cowboys to beat the New York Giants 30-17 on Sunday night despite playing without guard Tyler Smith.
Why it matters: For only the second Wednesday NFL opener in 107 years, Prisco's picks position the Seahawks as favorites in the Super Bowl rematch while spotlighting Mahomes' first start since his ACL tear and Aaron Rodgers' announced final-season debut — all 16 Week 1 games receive a prediction, setting early-season expectations league-wide.
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