Panthers vs. Lions predictions, odds, time: Week 4 'Sunday Night Football' picks by proven model — SkimNews

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- Lions-Panthers kicks off at 8:20 p.m. ET from Bank of America Stadium in Charlotte, with Detroit (2-1) a 3.5-point favorite over Carolina (1-2) and the over/under set at 51.5.
- The SportsLine projection model, which simulates each NFL game 10,000 times, projects 55 combined points and sees the Over hitting in 56% of simulations.
- Jahmyr Gibbs leads Detroit's ground game with 65 carries for 307 yards and four touchdowns through three games, anchoring an attack that produced 42 points in last season's meeting.
- Bryce Young powers Carolina's offense, completing 59.5% of passes for 939 yards, seven touchdowns and two interceptions heading into Week 4.
- Carolina receiver Jalen Coker (quad) is a game-time decision, while Xavier Legette (knee) was just placed on IR, thinning the Panthers' receiving corps.
- The Panthers have won six straight home games against Detroit dating back to 2002, though the Over has hit in five of the last eight head-to-head meetings and eight of Detroit's last 10 games overall.
Why it matters: The model's Over projection offers a contrarian lean against Carolina's 1-2 record and 21-18 Week 3 loss to Cleveland — Detroit's road scoring efficiency plus Bryce Young's seven passing touchdowns make the 51.5 total reachable despite Carolina's offensive injuries.
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