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- Buffalo Bills host the Detroit Lions on Thursday Night Football in Week 2, marking the club's debut at their new Highmark Stadium
- Bills beat the Houston Texans 36-31 in Week 1, sealing the win by forcing a C.J. Stroud fumble on the Texans' final drive
- Detroit Lions outlasted the New Orleans Saints 31-30 in overtime after the Saints rallied from a first-half shutout to tie it 24-24 at the end of regulation
- New Orleans Saints lost on a failed two-point conversion attempt after erasing what had been a Detroit shutout through the first two quarters
- Highmark Stadium is the Bills' brand-new home venue, replacing the prior Orchard Park facility, with Thursday marking its first NFL game
Why it matters: The matchup is the first game inside Buffalo's new Highmark Stadium, a long-anticipated venue replacement, and it doubles as a measuring stick between two 1-0 clubs whose Week 1 wins came on last-second defensive and special-teams plays — meaning either the Bills' new-home advantage or Detroit's overtime resilience gets validated in front of a national TNF audience.
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