College football odds, lines, schedule for Week 10: No. 1 Miami opens as road underdog at Notre Dame — SkimNews

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- Notre Dame opened as a 4.5-point favorite against top-ranked Miami in the slate’s biggest marquee matchup; despite its earlier loss to BYU, another defeat would leave zero margin for error in the playoff picture, while Miami’s secondary allowed Billy Edwards Jr. 341 yards in a 38-35 win over North Carolina.
- LSU opened -3.5 against No. 10 Alabama in Baton Rouge, with the loser in CFP jeopardy and LSU 1-6 in its last seven home games against Alabama; both teams are trying to avoid a third loss.
- Ohio State opened as a 10.5-point favorite over Oregon despite its loss to USC, with freshman quarterback Luke Fahey likely to start; Oregon quarterback Dylan Raiola has shown extreme highs and lows and tends to make mistakes when Ohio State’s defense applies pressure.
- Utah opened -4.5 against No. 8 BYU in the Holy War, scheduled for 10 a.m. local time, with both teams eyeing a Big 12 championship and a CFP spot; BYU carries a three-game winning streak in the rivalry.
- Texas opened -3.5 at Missouri, where quarterback Austin Simmons leads an explosive passing game and Ahmad Hardy has returned from an offseason gunshot wound to reinforce the run; Arch Manning would face more pressure if Colin Simmons remains sidelined.
- Tennessee opened -6.5 over Kentucky at Neyland Stadium; its defense has proven playoff-caliber, while its offense still has work to do after George MacIntyre’s two disastrous late plays against South Carolina.
- Georgia opened -3.5 at Ole Miss, a likely playoff eliminator for the Rebels; Georgia’s passing attack was ineffective against one of the SEC’s worst secondaries despite a 27-8 win over Florida, while Trinidad Chambliss gives Ole Miss a real shot at an upset.
Why it matters: For Notre Dame, a loss to top-ranked Miami would leave zero margin for error in the playoff picture even as the Irish carry a 4.5-point favorite line; Miami, meanwhile, enters after allowing Billy Edwards Jr. 341 yards and 38 points in a 38-35 win over North Carolina. The secondary matchup is therefore the concrete vulnerability behind the narrow line.
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