College football odds, lines, schedule for Week 7: Notre Dame opens as favorite in top-10 battle at BYU — SkimNews

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- Notre Dame opens as an 11.5-point road favorite at BYU in Week 7's only battle of undefeated top-10 teams — both squads need the result to bolster thin CFP resumes outside the power-conference bubble, and it's the first meeting in Provo since 2004 with both ranked for the first time in series history.
- Ohio State (-3.5) visits unbeaten Indiana (6-0) in a Big Ten Championship rematch, with the Hoosiers' perfect mark on the line against the 5-1 Buckeyes, who have won four straight since a Week 2 loss at Texas.
- Missouri heads to Ole Miss (-6.5) in a quarterback-revenge subplot, as former Rebels QB Austin Simmons returns to face his old team and successor Trinidad Chambliss in only the third meeting between the schools as SEC foes.
- Alabama (-6.5) travels to Tennessee seeking its first 'victory cigar' inside Neyland Stadium since 2020, while the Volunteers have dropped four straight home games against ranked opponents since beating the Tide in 2024.
- UCLA (5-0, 3-0 Big Ten) hosts Wisconsin (-3.5) coming off a stunning 17-15 win at Oregon, with first-year coach Bob Chesney's Bruins suddenly looking like a CFP contender against a Badgers team that has quietly improved to 4-1 since a Week 1 loss to Notre Dame.
- The 'best of the rest' slate stacks Auburn at Georgia (-18.5), Penn State at Michigan (-5.5), and Florida State at Miami (-20.5) as marquee power-conference matchups that will reshape the CFP picture alongside the headline game.
Why it matters: With both Notre Dame and BYU undefeated but operating on relatively weak schedules outside the Big Ten and SEC, a single loss likely knocks the loser out of the 12-team CFP field — turning this top-10 clash into a near-elimination game. The Week 7 slate doubles down on that pressure: Indiana can validate its 6-0 start against Ohio State, while Alabama tries to reassert itself at Tennessee and UCLA makes its playoff case against Wisconsin.
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