Oklahoma vs. Michigan prediction, odds, time: 2026 Week 2 college football picks by proven model — SkimNews

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- Oklahoma visits Michigan Stadium on Saturday at noon ET as a 5-point favorite, with the over/under set at 43.5 in the latest Week 2 lines.
- Michigan escaped Week 1 with a controversial 13-12 Hail Mary win over Western Michigan, while Oklahoma dismantled UTEP 51-0 and pitched a shutout with no points allowed even in garbage time.
- SportsLine's Projection Model simulated the matchup 10,000 times and projects 42 combined points, making the Under (43.5) its value pick — a play the model says hits 51% of the time.
- The model is also flagging one side of the spread as hitting well over 60% of the time, though that specific pick is gated behind SportsLine's paywall.
- The model sits on a 33-20 run on top-rated college football money-line picks since the 2024 season and has been upgraded for 2026 to better weight transfer-portal impact.
- Both defenses looked dominant in Week 1 — Michigan allowed just 13 points while Oklahoma allowed zero — which the model cites as the basis for its low-scoring projection.
Why it matters: Week 2 is the first real test for both programs before Big Ten and SEC play begins, and the model's Under lean puts a number on what could be a defense-driven grind: just 42 projected points against a 43.5 total. For bettors, the model's 33-20 money-line track record since 2024 gives the spread pick (60%+ hit rate) more weight than a typical projection blurb.
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