College football score predictions for Week 6, 2026: Model backing Kentucky (+8.5) against LSU — SkimNews
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- SportsLine's computer model simulates every FBS game 10,000 times and enters Week 6 on a 40-35 profitable run on top-rated college football picks at betting sites.
- The model projects LSU to beat Kentucky 25-21, with Kentucky (+8.5) hitting as the play against the spread in 53% of simulations and the Under (50.5) clearing with room to spare.
- Kentucky under head coach Will Stein has won and covered in three straight games, including outright upset wins over SEC opponents South Carolina and Texas A&M.
- Lane Kiffin's LSU squad is projected to win on the road but fail to cover the double-digit spread at Kentucky.
- No. 6 Alabama hosts No. 2 Georgia at 7:30 p.m. ET Saturday as a 1.5-point home favorite, a 4-point swing from Georgia opening at -3.
- The Week 6 slate also features No. 13 Oregon (-11.5) vs. No. 21 UCLA, USC vs. Penn State (-1.5), Texas vs. Oklahoma (+8.5) in the Red River Rivalry, and unbeaten Indiana at Nebraska (+7).
Why it matters: Backers of **Kentucky (+8.5)** at LSU get a model that projects only a 4-point LSU win margin, while the Wildcats arrive on a three-game streak of winning and covering that includes upset wins over SEC opponents South Carolina and Texas A&M. A 4-point projected margin against an 8.5-point spread is the kind of mismatch between projection and market line the SportsLine model has profited on during its 40-35 run.
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