Buffalo vs. Miami (Ohio) prediction, odds, time: Week 10 MACtion college football picks from proven model — SkimNews

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- SportsLine simulated the matchup 10,000 times, selected the Over 44.5, projected 50 combined points and found the Over was the value side 64% of the time.
- SportsLine simulates every FBS game 10,000 times and entered Week 10 on an 80-77 run across its top-rated college football picks at betting sites.
- Miami (Ohio) is the 6.5-point favorite in a game with a 44.5 total, scheduled for 8 p.m. ET at Fred C. Yager Stadium in Oxford, Ohio.
- Buffalo enters at 5-3 overall and 3-1 in MAC play, tied for third with Miami, but stands 1-2 on the road after a 31-24 win over Bowling Green on Oct. 24.
- Miami (Ohio) is also 5-3 overall and 3-1 in the MAC, has won three straight and is 3-1 at home in 2026 after beating Central Michigan 28-27 on Oct. 24.
- Miami (Ohio) leads the all-time series 18-9 and won last year’s meeting 37-20; the RedHawks rank third in MAC scoring at 27 points per game, while Buffalo is sixth at 22.6.
- Jason Wright is projected for more than 175 passing yards and one touchdown after throwing for 987 yards and seven scores, while Caleb Heavner is projected for more than 215 yards and two touchdowns.
Why it matters: For bettors, the clearest split is the Over 44.5: SportsLine selects it in 64% of simulations and projects 50 combined points, while Miami (Ohio) is the 6.5-point favorite. The article discloses the total but leaves the model’s spread and moneyline choices behind a SportsLine link.
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