Texas A&M nasal spray reverses brain aging in study
SkimNews Take
The nasal delivery method for brain-targeting microRNAs demonstrates a novel strategy for bypassing the blood-brain barrier, potentially opening new non-invasive avenues for neurological treatments beyond age-related decline.
Get the Health newsletter
Daily health & science — research, biotech, public health, the studies worth knowing. Free.
- Texas A&M University researchers created a nasal spray that delivers extracellular vesicles loaded with microRNAs directly to brain tissue via intranasal administration.
- The spray lowered chronic neuroinflammation and reactivated brain energy pathways after only two doses in the study.
- Study participants showed improved memory and cognitive performance that persisted for months after treatment.
- The research was published in the Journal of Extracellular Vesicles and was led by Dr. Ashok Shetty, Dr. Madhu Leelavathi Narayana, and Dr. Maheedhar Kodali.
- Researchers suggest the approach could become a new therapeutic avenue for age‑related neurodegenerative diseases such as dementia and Alzheimer’s.
Why it matters: Patients could receive only two nasal spray doses and experience memory gains lasting months, reducing the need for ongoing medication and lowering dementia care costs.
