Ohio State 2.5-point road favorites at No. 5 Indiana — SkimNews
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- Ohio State opened as a 2.5-point road favorite over No. 5 Indiana for Saturday's noon ET kickoff at Memorial Stadium in Bloomington, with the over/under set at 49.5 and juiced to the under.
- Saturday marks the 100th all-time meeting between the programs since 1901 and the third straight AP Top-5 matchup after zero such matchups in the first 97 games.
- Indiana enters on a 22-game winning streak — its last loss was the first round of the 2024 College Football Playoff — and defeated Ohio State in the 2025 Big Ten Championship Game.
- Jeremiah Smith is one receiving touchdown from the Big Ten career record (39) and leads the Heisman Trophy odds, while quarterback Julian Sayin is 12-0 as a regular-season Big Ten starter.
- Head coaches Curt Cignetti (.897) and Ryan Day (.870) combine for the highest career win percentage between coaches entering a regular-season FBS matchup (minimum 30 games coached), per the source.
- SportsLine expert Brad Thomas took Ohio State -3 on Monday and said he's comfortable with the moneyline under -185, citing Indiana's 63% completion rate allowed and 127th national ranking in explosive plays allowed as matchup vulnerabilities for the Hoosiers.
Why it matters: With Ohio State a 2.5-point road favorite and SportsLine's Brad Thomas specifically targeting the matchup between Heisman leader Jeremiah Smith and Indiana's 127th-ranked explosive plays allowed, bettors at DraftKings get concrete handicapping data beyond the spread — and a 22-game Hoosier winning streak plus 12-0 Big Ten record for Sayin give each side a credentialed angle.
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