Ohio State vs. Indiana prediction, odds, time: Week 7 college football picks by proven model — SkimNews
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- Ohio State (5-1) visits Indiana (6-0) at noon ET Saturday at Memorial Stadium in Bloomington, with the Buckeyes installed as 3-point road favorites and the total set at 50.5.
- SportsLine Projection Model ran 10,000 simulations and projects 51 combined points, pegging the Over 50.5 as a value play that hits 51% of the time.
- The model says one side of the spread hits in 60% of simulations — a pick gated behind SportsLine's paywall.
- Ohio State starts quarterback Julian Sayin and receiver Jeremiah Smith, both Heisman contenders, but running back Ja'Kobi Jackson has been ruled out.
- Indiana counters with TCU transfer quarterback Josh Hoover, who has guided the Hoosiers through close calls to stay unbeaten this season.
- Indiana upset Ohio State 13-10 in last year's Big Ten title game — the program's first win in the series since 1988 — giving the defending national champs a recent edge in the matchup.
- SportsLine's model enters Week 7 on a 48-40 run on top-rated college football picks, reportedly returning more than $400 for $100 players.
Why it matters: The SportsLine model is 48-40 on top-rated CFB picks, and its 60% confidence spread lean on a game where the defending national champion (Indiana) beat Ohio State 13-10 last year in the Big Ten title game despite Ohio State now laying 3 points on the road — a notable line that reflects bookmakers giving the Buckeyes credit their recent head-to-head results don't support.
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