Knicks vs. Pistons prediction, odds, time: 2026 NBA picks for Tuesday, Oct. 27 from advanced model — SkimNews

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- New York Knicks host the Detroit Pistons at 8 p.m. ET on Tuesday, Oct. 27, from Madison Square Garden, with New York listed as a 4.5-point favorite and the over/under set at 219.5.
- Detroit Pistons opened the season 3-0 while the defending-champion Knicks went 0-3, making New York just the third defending champion to start the following year winless through three games.
- New York Knicks went 0-3 against Detroit last season despite winning the title, with the Pistons the only Eastern Conference team not to lose to them; Detroit has since won each of the last six regular-season matchups.
- Jalen Duren is out for Detroit with a hamstring injury, and the model points to that absence helping the Knicks put points on the board, projecting all five New York starters scoring in double figures.
- SportsLine Projection Model is going Over on 219.5, hitting in 57% of 10,000 simulations with a 225-point forecast, and also projects eight Detroit players scoring at least 8 points.
- Madison Square Garden matchups have run hot: the last four cleared the 219.5 total, and seven of the last eight meetings went over by at least six points, five of them by double digits.
- SportsLine Projection Model enters Week 2 of the 2026-27 season on a 26-10 (72%) run on top-rated spread picks, having returned nearly $19,000 on $100 since 2018 across five straight four-digit-profit seasons.
Why it matters: Bettors get one actionable line out of the model: Over 219.5, which lands in 57% of 10,000 simulations with a 225-point projection. The framing is Knicks revenge, but the spread pick is deferred to a SportsLine link, so the usable angle is scoring volume — five Knicks starters in double figures with Jalen Duren sidelined — rather than New York's 4.5-point favorite status.
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