Cochrane: Vapes Beat Patches, Gum for Quitting Smoking — SkimNews

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- Cochrane released an updated living systematic review of 80 randomized controlled trials (29,861 participants, 9 new in this update) finding nicotine e-cigarettes produced higher quit rates than nicotine patches, gum, behavioral support, or no support.
- Nicotine e-cigarettes yielded about 4 additional successful quitters per 100 people versus nicotine replacement therapy — high-certainty evidence — and about 2 additional quitters per 100 versus non-nicotine e-cigarettes.
- Dr. Jamie Hartmann-Boyce, senior author at the University of Massachusetts Amherst, called regulated nicotine e-cigarettes "substantially less harmful than smoking" and "a proven and viable option" for people wishing to quit traditional cigarettes.
- Researchers found no evidence that using e-cigarettes to quit increased the risk of serious harm, though they stressed longer-term research is still needed and the conclusions apply only to regulated, nicotine-containing devices, not illicit or THC-containing products.
- Hartmann-Boyce warned that unlicensed e-cigarettes are "potentially dangerous" with issues including unstable batteries and harmful chemicals, urging consumers to use only devices approved by regulators like the FDA or MHRA.
- Dr. Nicola Lindson, lead author at the University of Oxford, emphasized that quitting is hard and having multiple options matters, framing vaping as less harmful than continued smoking but not risk-free.
- The WHO continues to warn that e-cigarettes expose users to nicotine and other harmful chemicals, and health officials have raised concerns that youth vaping can lead to nicotine addiction and later tobacco use.
Why it matters: For the roughly seven million people killed annually by smoking worldwide, the review strengthens the case that regulated vaping is a meaningfully more effective cessation tool than patches or gum — about 4 extra quitters per 100. But the authors and WHO both stress vaping is a transition step, not an endpoint, and unregulated devices remain a documented hazard.
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