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Moderna, Merck say mRNA cancer vaccine slowed melanoma recurrence
Merck and Moderna said Wednesday that their personalized mRNA neoantigen vaccine, intismeran, slowed melanoma recurrence in the first randomized Phase 3 trial ever run for a neoantigen cancer vaccine,
Yeast beta-glucan boosts cancer immunity in mice
Trinity College Dublin and UCD researchers report that a yeast-based dietary supplement, taken orally rather than by injection, reprogrammed bone marrow immune cells to produce trained anti-tumor resp
‘Off the charts’ El Niño is already the strongest since records began
Climate scientist James Hansen says the developing El Niño has already surpassed the 1997-98 super event by his preferred deep-ocean heat metric, though experts disagree over whether the more common s
STAT+: HHS document offers new clues to Kennedy’s vaccine plans
HHS posted a request for information Friday seeking public comment on restructuring the childhood vaccine recommendation framework, giving the public 30 days to weigh in on whether new categories shou
Greenland Meltwater Driving European Heatwaves: Study
A peer-review study finds Greenland ice sheet meltwater is cooling the North Atlantic and shifting the jet stream, intensifying heatwaves across western Europe and the Mediterranean beyond what curren
Burns improve more rapidly after treatment with fish skin
A study of 465 burn patients across 49 centers found that cod-skin grafts from Kerecis reduced hospital stays by 12 days and halved complication rates compared with synthetic substitutes, with researc
Spruce Biosciences Hires Adrian Quartel as CMO
STAT+'s recurring "Up and down the ladder" personnel-moves column this week highlights Spruce Biosciences' hire of Adrian Quartel as chief medical officer, a role he most recently held at Zevra Therap
3 minutes of sprinting does something 90 minutes of exercise does not
Rockefeller University researchers found that just three minutes of all-out sprinting reshaped nearly a quarter of measured blood proteins and over 200 metabolites, a molecular surge that 90 minutes o
This weight-loss hormone may protect the liver even without weight loss
McMaster University researchers discovered that GDF15, a hormone already used in weight-loss drugs, protects the liver from inflammation through a newly identified brain-to-liver signaling pathway — i
AI Predicts Vaccine Response from Antibody Patterns
AI analyzed pre-vaccination antibody patterns in over 4,000 people, revealing 'immune readiness' markers that predict how strongly individuals will respond to vaccines before receiving them.
Ebola outbreak: five big questions
The DRC's Ebola outbreak has grown to nearly 5,000 cases and over 2,000 deaths since May, making it the country's largest and deadliest on record, with 850 people who tested positive now unaccounted f
HIV Cure Raises Benefits Cliff Risk for Survivors
Three HIV researchers and advocates warn that as cure research advances toward clinical reality, long-term survivors could lose Medicaid, Medicare, Ryan White services, disability income, and housing
Study: Drought Boosts Cholera, West Nile, and Dengue Spread
A new review of nearly 100 studies surfaces the 'drought-disease paradox' — diseases like cholera, West Nile virus, and dengue can boom as the world dries, reshaping how scientists forecast outbreaks.
Lil Nas X: treatment freed his creativity, not dulled it
An opinion piece by Rachel Docekal, CEO of the Hanley Foundation, argues that high-achieving people resist mental health treatment because they conflate emotional suffering with the source of their su
Focal Prostate Cancer Therapy Splits Doctors on Long-Term Data
Focal therapy for localized prostate cancer shows 10-year survival outcomes comparable to surgery or radiation with fewer side effects, yet the American Urological Association still labels it experime
How long could we possibly live? A new estimate is mind-boggling
Estimates of maximum human lifespan range from 115 to 194 years, but a new book argues the supercentenarian data underpinning those figures is corrupted by pension fraud and clerical errors — leaving
Home Screening Cuts Colorectal Cancer Death Risk 43%
A long-term Swedish study of more than 376,000 people found that participating in at-home colorectal cancer screening cuts the risk of dying from the disease by 43%, compared with 26% for those merely
Cutting Air Pollution Cuts Heart Hospitalisations
Real-world cases from Greece, the United States and the United Kingdom show that cutting air pollution through mine closures and clean air zones produced immediate, measurable drops in heart-related h
Butyrate 'Trains' Gut Cells for Lasting Protection
A Northwestern Medicine study published in Nature Communications shows that butyrate — produced when gut bacteria break down dietary fiber — reprograms intestinal cells to sustain anti-inflammatory im
Ozempic Activates Hunger Neurons to Sustain Fat Loss: Yale
Yale researchers discovered that Ozempic and similar GLP-1 drugs activate — rather than suppress — the brain's hunger-driving AgRP neurons in mice, and that these neurons appear essential for sustaini
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