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Akero Team Launches Avere Therapeutics with Fairmount
The former leadership of Akero Therapeutics has launched Avere Therapeutics, a new biotech firm backed by Fairmount, to develop an oral IL-23 inhibitor for immunological diseases like psoriasis and ul
Eating chili peppers may raise the risk of one deadly cancer
A meta-analysis of 14 studies found heavy chili pepper consumption linked to a 64% higher overall risk of gastrointestinal cancers, with the strongest signal—nearly triple the risk—appearing in esopha
Biogen Alzheimer’s Drug Slows Decline, Lowers Tau
Biogen's experimental Alzheimer’s drug diranersen slowed cognitive decline in a mid-stage trial at rates similar to approved therapies, supporting plans for a Phase 3 study and renewing debate over wh
NASA, ESA Fund Human Hibernation Research for Mars
NASA- and ESA-funded researchers around the world are racing to develop ways to induce synthetic torpor in humans, a feat that could protect astronauts from radiation, muscle loss, and the 300kg of fo
FDA Approved Zyn Pouches Without Knowing What They’re Made Of
A former FDA toxicologist says the agency approved Zyn nicotine pouches without knowing what the pouch material was made of, despite her warnings that it could pose health and environmental risks from
After AlphaFold: Drug AI Targets PXR Activation
Drug developers are shifting AI ambitions past protein-folding toward predicting whether the pregnane X receptor — whose enzyme metabolizes roughly 50% of all marketed drugs — will activate against a
Deepfakes impersonate doctors to sell unregulated treatments
Deepfake technology is being used to impersonate doctors in synthetic videos promoting unregulated treatments, threatening trust in digital healthcare and raising urgent concerns about authenticity in
Scientists Find Neural Circuit for Mechanical Itch
University of Michigan researchers have discovered a dedicated neural circuit in mice that detects mechanical itch through fine vellus-like hairs, with evidence suggesting humans have a similar system
Yale discovers hidden electrical network in the retina
Yale School of Medicine researchers have discovered that electrical synapses weave most of the retina's separate visual channels into a single coordinated network, with a 'commander' bipolar cell call
Maya mathematician’s name decoded alongside astronomical formula
Researchers have decoded the name of Sak Tahn Waax, a Maya astronomer-mathematician who lived ~1,200 years ago, inscribed beneath a complex formula predicting the orbital cycles of Mars and Venus in a
Study: Menstrual Cycle Worsens ADHD Symptoms
A new UK study is investigating how hormonal changes during the menstrual cycle worsen ADHD symptoms in women, challenging the current understanding of how medication efficacy fluctuates across the mo
AIDS Activists Slam Biden-Gilead HIV Drug Patent Deal
AIDS activists obtained the R&D agreement at the center of a settlement between the U.S. government and Gilead Sciences over HIV prevention drug patents, but say the Biden administration squandered a
Humans doubled body mass over 4.5 million years
An analysis of 386 hominin fossils published in PNAS shows average human body mass rose from 40 kg to 75 kg over 4.5 million years, with the biggest jump coinciding with the emergence of Homo erectus
Latin American Study Replicates U.S. Pointer Dementia Findings
A Latin American dementia study presented at AAIC replicates the U.S. Pointer trial's finding that intensive, structured lifestyle interventions — covering diet, exercise, and cardiovascular monitorin
STAT+: UnitedHealth’s questionable review, and more MA stars lawsuits
UnitedHealth Group promoted an audit finding that 97% of diagnoses from its Medicare Advantage members' home visits were medically justified, but STAT+ reported the results aren't as clean or useful a
80 Minutes Less Sleep a Night Linked to Weight Gain
A Columbia University study found that adults who lost about 80 minutes of sleep per night for six weeks gained roughly a pound and became more sedentary — evidence that mild, chronic sleep loss can s
Brain Makes Decisions Earlier Than Thought
Scientists discovered that decision-making in the brain begins earlier than previously thought, with primary sensory regions involved via rapid feedback loops from higher brain areas.
USC Study Links Healthy Diets to Lung Cancer Risk
A USC study finds young non-smokers with healthier diets may face higher lung cancer risk, prompting investigation into pesticide exposure from conventionally grown produce.
Where you live could shape your dementia risk, massive study finds
A USC-led study of more than 214,000 older adults across 14 countries found that dementia risk factors vary dramatically by nation, suggesting prevention strategies must be tailored locally rather tha
Gum Disease Bacterium Found in Calcified Heart Valves
Preliminary research presented at an American Heart Association meeting links Porphyromonas gingivalis — a bacterium behind gum disease — to calcium buildup in the aortic valve, suggesting a biologica
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