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FDA Approves Vera's Trutakna for IgA Nephropathy
The FDA approved Vera Therapeutics' Trutakna to treat IgA nephropathy, a chronic autoimmune kidney disease caused by immune antibody buildup that can progress to organ failure and dialysis.
Men’s average testosterone levels have halved in last 50 years, say scientists
A meta-analysis of six longitudinal studies covering 118,593 men across five countries found total testosterone levels dropped 54% between 1972 and 2019, with the decline accelerating after 2000.
U.S. Employer Health Insurance Is At Its Worst, STAT Says
STAT is launching a new series called 'Out of Pocket, Out of Reach' examining how the U.S. employer-based health insurance system is crumbling, with the outlet describing conditions as 'arguably never
STAT+: Pharmalittle: We’re reading about a $10 billion Vertex deal, the pace of FDA drug approvals, and more
Vertex Pharmaceuticals will spend $10 billion to acquire Crinetics Pharmaceuticals and its recently launched rare-disease drug Palsonify, marking the largest deal in Vertex's history as the Boston bio
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Mass Balance Sends Self-Running Lab to Orbit on SpaceX
British startup Mass Balance launched a grapefruit-sized autonomous laboratory on a SpaceX transporter to test whether microgravity can yield cleaner data on disease-causing disordered proteins linked
NHS GPs to Offer Two New Endometriosis Tests
Draft guidance for the NHS in England and Wales would let GPs offer two non-invasive tests — a saliva spit test and a gut electrical-signal test — alongside standard checks to help identify endometrio
Obamacare Enrollment Plunges 3M After Subsidy Expire
Obamacare enrollment has plunged roughly 3 million people (about 13%) nationally since enhanced federal subsidies expired, with the steepest losses concentrated in Ohio, Oklahoma, Arizona, South Carol
Opinion: What if this Ebola outbreak can’t be stopped?
Two former Médecins Sans Frontières leaders warn that a new Ebola outbreak in eastern Democratic Republic of Congo may never be contained, citing weakened WHO and CDC capacity, a regional proxy war ov
Opinion: Medicine thinks Gen Z is too soft. It’s wrong
A health care executive argues that medicine's 'Gen Z is too soft' narrative misdiagnoses the real problem: a workforce being ground down by broken workflows, with an 86,000-physician shortfall loomin
Georgia entrepreneur Amy Bielawski has never been able to afford
A STAT+ profile spotlights Amy Bielawski, a 61-year-old Tucker, Ga. entrepreneur who has gone most of her life without health insurance while running her own entertainment company for 32 years.
Small Businesses Ditch Health Insurance as Costs Soar
America's small businesses are abandoning employer-sponsored health insurance at an unprecedented pace as premiums soar, eroding the backbone of the U.S. employer-based coverage system that still insu
STAT+: This whistleblower took on a health insurance giant and a political machine. She’s not stopping there
Chris Deacon, the New Jersey health-plan official who investigators say drove a $100 million settlement against Horizon Blue Cross Blue Shield over alleged healthcare fraud, watched officials tout the
Ovaries become immune organs after menopause: mouse study
New research shows that ovaries in ageing mice become infiltrated with immune cells and shift away from their reproductive signature, suggesting they may actively contribute to chronic inflammation af
Mouse ovaries shift to immune-like function after reproduction
A Northwestern University study in mice found that ovaries transform into an "immune-like organ" after reproduction ends, with inflammation-linked genes activating and immune cells multiplying. The fi
Air pollution linked to DNA changes in sperm, research shows
A study of more than 2,000 men in Salt Lake City found that exposure to common air pollutants — particularly ozone and nitrogen dioxide — was associated with epigenetic changes in sperm DNA that could
STAT+: Vertex acquires Crinetics Pharmaceuticals for $10 billion as biotech M&A booms
Vertex Pharmaceuticals announced a $10 billion deal to acquire Crinetics Pharmaceuticals, gaining its commercial acromegaly drug Palsonify and a late-stage pipeline candidate for congenital adrenal hy
Bee Tongue Movements Reveal 'Wanting' vs 'Liking'
A Macquarie University study found bumblebees extend their tongues in patterns that separate the motivation to seek food from the pleasure of eating — the strongest behavioral evidence yet that insect
Turkey cave artefacts hint Neanderthal-human exchange
Archaeological excavations at Üçağızlı II cave in Turkey reveal that Neanderthals and Homo sapiens maintained remarkably consistent stone-tool technology and both collected ornamental Columbella rusti
Obamacare rolls shrank dramatically in many states over the past year, new federal data shows
New federal data shows roughly 2.6 million Americans lost Affordable Care Act coverage year-over-year after pandemic-era enhanced subsidies expired, with some states shedding more than a third of thei
Brain Health Monitoring Goes Proactive With New Biomarkers
A new wave of tools — from Alzheimer's blood tests and genetic panels to heart-rate-variability tracking on smartwatches — promises to monitor brain health proactively, though experts caution most are
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