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The Readout LOUD Flags AI Longevity, Chinese Biotech
In a recent episode of The Readout LOUD, hosts unpacked the biotech landscape from the STAT Breakthrough Summit West, spotlighting BridgeBio’s own concerns about research rigor, Retro Biosciences’ AI‑
Early junk‑food diet rewires brain; probiotic helps
A University College Cork study shows that high‑fat, high‑sugar diets in early life permanently alter brain appetite circuits in mice, yet probiotic and prebiotic treatments can partially restore heal
STAT+: Pharmalittle: We’re reading about a Lilly obesity drug trial, statistics for an Alzheimer’s drug, and more
Eli Lilly’s next‑generation obesity pill delivered weight loss rivaling bariatric surgery—28 % on average—but an 11 % adverse‑event dropout rate exceeds the 7 % seen with competitors, casting doubt on
GLP‑1 drugs cut heart attacks and strokes by 13%
A comprehensive meta‑analysis of 11 cardiovascular outcome trials shows that GLP‑1 receptor agonists significantly cut major heart events, strokes and premature deaths by roughly 13% in over 90,000 hi
Chlorpyrifos Exposure Linked to Child Brain Damage
Prenatal exposure to the pesticide chlorpyrifos is linked to lasting brain structural, functional, and metabolic changes and reduced motor performance in children, according to a new JAMA Neurology st
Women’s better memories may delay Alzheimer’s diagnosis by years
A new study shows that women’s stronger verbal memory can conceal early Alzheimer’s pathology, letting them score normally on standard tests for nearly three years longer than men. This hidden reserve
PerturbFate Finds Shared Hubs Across Cancer Mutations
Scientists at Rockefeller University unveiled PerturbFate, a single‑cell tracking platform that maps how hundreds of cancer‑linked mutations converge on common regulatory hubs. By testing the system o
STAT+: Lilly’s ‘triple-G’ drug leads to bariatric-surgery levels of weight loss in trial
Eli Lilly’s experimental obesity drug retatrutide delivered an average 28.3% weight loss in a Phase 3 trial, approaching the results of bariatric surgery. However, 11% of participants on the highest d
Lyme disease cases in England rise by more than 20% in a year
England’s Lyme disease burden surged by over 20% in 2025, with the UK Health Security Agency confirming 1,168 cases – a jump from 959 the year before and comparable to 2023 levels. The agency also fla
Leucine Boosts Mitochondria via SEL1L Pathway
University of Cologne researchers discovered that the amino acid leucine enhances mitochondrial energy production by protecting outer-membrane proteins from degradation via the SEL1L pathway, with pot
SpaceX Files for Record IPO on Nasdaq as SPCX
SpaceX filed publicly for what would be the largest-ever IPO on Nasdaq under the symbol SPCX, with Elon Musk's shares giving him 85.1% of the voting power.
Imperagen raises £5 million to use quantum physics, AI on enzyme engineering
Imperagen, a Manchester‑based biotech spin‑out, secured £5 million in seed funding to accelerate its quantum‑physics‑driven, AI‑powered enzyme‑engineering platform. By coupling massive simulation of e
MacKenzie team files IND for fetal gene therapy trial
After a quarter‑century of successful mouse experiments, Tippi MacKenzie’s team has filed an IND to treat five fetuses with a rare lysosomal storage disorder. The FDA has waived additional animal test
Surgeon General Issues Screen‑Time Warning for Kids
The U.S. Surgeon General’s Office, under Health Secretary Robert F. Kennedy Jr., released a draft advisory urging a sharp cut to children’s screen time, echoing earlier Biden‑era concerns. The report
Researchers Probe Quantum Effects in EM‑Field Therapies
Emerging clinical research shows that light, electric and magnetic field exposures can improve conditions from acne to cancer, yet scientists admit the underlying mechanisms remain mysterious. Experts
FDA turnover fuels investor anxiety over rare drugs
Biotech leaders and an academic specialist warn that recent FDA leadership shake‑ups are shaking confidence in rare‑disease drug pipelines, with CEOs fielding daily investor questions about approval t
Parabilis Medicines IPO; FDA Names New Interim Chief
Biotech firm Parabilis Medicines is stepping onto the public market as the FDA undergoes a leadership shift, with former commissioner David Kessler voicing confidence in interim chief Kyle Diamantas.
Kennedy names Stephanie Haridopolos interim surgeon
Robert F. Kennedy Jr. reshuffled his health team, naming family‑medicine doctor Stephanie Haridopolos as interim surgeon general while also removing two leaders from the preventive services task force
Dawkins' Selfish Gene Turns 50, Still Influential
The Selfish Gene, Richard Dawkins’ 1976 gene‑centred evolution classic, marks its 50th anniversary with a new epilogue, reaffirming its lasting influence while sparking renewed discussion over its met
Bees spend as much energy buzzing pollen as flying
Bumblebees expend as much energy vibrating flowers to release pollen as they do taking flight, a study reveals, highlighting the high cost of buzz pollination and its implications for bee foraging und
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