Boosting one protein helps the brain fight Alzheimer’s

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- Sox9 activation in astrocytes reduced amyloid plaque buildup and maintained cognitive performance in mice with established Alzheimer’s symptoms.
- Baylor College of Medicine researchers published the findings in Nature Neuroscience on May 2 2026, highlighting a novel cell‑based approach to neurodegeneration.
- Dr. Dong‑Joo Choi led the work at the Center for Cell and Gene Therapy and now serves as an assistant professor at the University of Texas Health Science Center at Houston, emphasizing astrocyte aging in disease.
- Dr. Benjamin Deneen directed the study, noting that Sox9 regulates many genes in aging astrocytes and could be a target for slowing cognitive decline.
Why it matters: Not enough in the article to say why this matters.




