NFL Week 1 parlays: Eagles, Bears, Chargers as favorites — SkimNews

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- Seattle Seahawks opened the NFL season Wednesday by beating the New England Patriots 13-10.
- Mike Tierney of SportsLine released two three-team money line parlays for Week 1, going 320-271-16 over four seasons and 130-101 ATS the past two.
- The favorites parlay features the Bears over the Panthers, Eagles over the Commanders, and Chargers over the Cardinals.
- Eagles coach Nick Sirianni is 5-0 in Week 1 openers, while the Commanders fielded the NFL's most porous defense in 2025 and lost QB Jayden Daniels to injuries.
- The underdogs parlay backs the Texans over the Bills, Jets over the Titans, and Broncos over the Chiefs.
- Texans coach DeMeco Ryans is 4-1 against Josh Allen-led Bills, with Allen going 9-for-30 in their 2024 meeting and absorbing eight sacks last season.
- Denver finished eight games ahead of Kansas City in last year's AFC West standings, has won three straight in the rivalry, and returns the league's top sack defense virtually intact.
Why it matters: Tierney's Denver underdog pick rests on concrete numbers: the Broncos finished eight games ahead of Kansas City last season, have won three straight in the series, and return the league's top sack defense intact. For bettors weighing the Chiefs' Super Bowl pedigree against Denver's divisional dominance, it's a data-backed contrarian play rather than a vibes call.
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