Alabama vs. South Carolina prediction, odds, time: 2026 Week 4 college football picks by proven model — SkimNews
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- No. 8 Alabama enters the matchup at 3-0 (1-0 SEC) after dismantling Florida State 50-36, with sophomore QB Keelon Russell throwing for 320 yards in the win.
- South Carolina comes in at 2-1 following a 41-34 home loss to Mississippi State, despite junior QB LaNorris Sellers posting 282 passing yards.
- Alabama is a 12.5-point favorite over the Gamecocks with the over/under set at 54.5 points for the 7 p.m. ET kickoff at Bryant-Denny Stadium.
- Alabama will be without edge rushers Justin Hill and Desmond Umeozulu, who have been ruled out for the game.
- The SportsLine Projection Model projects the Under (54.5), calling for 42 combined points, with the Under hitting in 59% of its 10,000 simulations.
- SportsLine's model is off to a 22-19 start on top-rated college football picks this season and was upgraded for the 2026 season to better factor in the transfer portal.
Why it matters: For bettors, the model identifies a clear lean: Under 54.5 hits in 59% of simulations despite Alabama's explosive offense, because South Carolina's inconsistent attack and physical SEC environment keep scoring suppressed. Alabama's injury-depleted edge rush (Hill and Umeozulu out) could pressure Sellers but also limits the Tide's pass-rush upside.
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