Week 5 NFL odds, picks, predictions: Computer model backs Vikings and Bengals — SkimNews

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- SportsLine's computer model simulates every NFL game 10,000 times and has returned more than $7,000 for $100 players on top-rated NFL picks since its inception.
- The model entered Week 5 of the 2026 NFL season on a 55-44 run on top-rated picks dating back to 2024, per the source.
- Seahawks vs. 49ers is the only Week 5 matchup featuring teams over .500, with Seattle favored by 3 points at home.
- Vikings (-1.5, total 42) are projected to cover at the Saints in over 60% of simulations, riding a nine-game win streak and an 8-1 record against the spread over that span.
- Saints backers face steep history: New Orleans is 1-5 ATS in its last six as a home underdog and is coming off a short week.
- Bengals (-7.5, total 42.5) are picked to cover at the Dolphins in well over 50% of simulations, with Miami owning the NFL's 32nd-ranked scoring offense and scoring exactly one touchdown per game.
- Joe Burrow carries a 132.8 career passer rating versus Miami, the highest of any opponent he has faced, and the model forecasts 47 total points in the matchup.
Why it matters: SportsLine's model gives bettors data-driven picks during a uniquely compressed Week 5 slate — only one of the week's games pits winning teams against each other — meaning every remaining matchup offers sharp line value to anyone backing its projections against the spread.
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