Kentucky vs. LSU odds, picks, predictions, time, line: Betting preview for college football Week 6 on Saturday — SkimNews

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- No. 10 LSU visits Kentucky on Saturday as a 9.5-point favorite in an SEC Week 6 matchup (7 p.m. ET, Kroger Field), per DraftKings
- Kentucky enters on a three-game winning streak after rallying from a 17-0 deficit to beat South Carolina 35-34 in overtime; the Wildcats also upset Texas A&M earlier this season as a 17-point underdog
- LSU has won two straight since its only loss — a 32-24 road defeat at then-No. 8 Ole Miss on Sept. 19 — including a 63-14 rout of McNeese State where QB Sam Leavitt did not play in the second half
- LSU leads the SEC in total offense (547.8 yards per game) and in yards allowed per game on defense, but will be without linebacker Whit Weeks and tight end Trey-Dez Green, both sidelined indefinitely
- SportsLine Projection Model projects LSU winning by four points, with Kentucky covering the 9.5-point spread in 62% of its 10,000 simulations; the model is on a 40-35 run on top-rated CFB money-line picks this season
Why it matters: DraftKings lists LSU as a 9.5-point road favorite despite the Tigers' lone loss coming on the road at Ole Miss and two defensive starters (Weeks, Green) sidelined indefinitely — the SportsLine model that is 40-35 on top-rated CFB money-line picks projects LSU winning by just four and Kentucky covering in 62% of 10,000 simulations, putting the spread in sharp conflict with the model's simulated margin.
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