15 NFL Week 2 Predictions: Upsets, Sleepers, Stat Lines — SkimNews

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- Buffalo Bills opened Week 2 with a 41-31 win over the Detroit Lions at Highmark Stadium, leaving 15 games still to play across Sunday and Monday.
- Betting analyst Pamela Maldonado flagged two underdogs: the Jacksonville Jaguars +124 at Denver (Broncos managed just 176 yards vs. Kansas City) and the Cincinnati Bengals +120 at Houston (Burrow sacked only once, while the Texans allowed 10.4 yards per pass to Buffalo).
- Analytics writer Seth Walder projected Rhamondre Stevenson for 16 carries, 63 rushing yards, 5 receptions, 42 receiving yards, and 1 receiving TD — anchored by Pittsburgh running zone coverage 89% of the time under new defensive coordinator Patrick Graham.
- Derrick Henry rushed for three touchdowns in Baltimore's Week 1 win under new OC Declan Doyle's schemed zone concepts and tight-end motion, and Matt Bowen projects another score against a Saints defense that allowed two rushing TDs in Week 1.
- Fantasy writer Eric Moody flagged Caleb Douglas (rostered in 34.9% of ESPN leagues) after the rookie caught 5 of 7 targets for 94 yards in his debut; Miami enters as double-digit underdogs against San Francisco, setting up a pass-heavy script.
- Ben Solak predicted the Jets will finally record an interception — their last pick was Jan. 5, 2025, 623 days ago — banking on Minkah Fitzpatrick against a Packers pass protection that surrendered 16 hits on Jordan Love in Week 1.
- Solak also flagged undrafted DII free agent Jack Strand (Minnesota State-Moorhead) as a sneaky touchdown scorer on QB sneaks if Atlanta reaches the 2-yard line against Carolina.
Why it matters: The Jaguars and Bengals carry plus-money upset odds (both +120 or better), Caleb Douglas sits rostered in only 34.9% of ESPN leagues as a Week 2 sleeper, and the Jets target their first interception in 623 days against a Packers team whose QB absorbed 16 hits in Week 1 — concrete, source-attested data points fantasy managers and bettors can act on immediately.
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