Cardinals vs. 49ers predictions, NFL picks: Get a $55 bonus by using the latest Kalshi promo code CBSSPORTS55 — SkimNews
Get the Sports newsletter
Daily sports — scores, transfers, the storylines from the leagues you actually follow. Free.
- San Francisco 49ers (2-0) host the Cardinals at Levi's Stadium Sunday at 4:05 p.m. ET, with Kalshi pricing a Niners win at $0.78 per share versus $0.23 for Arizona.
- Brock Purdy has thrown for 492 yards with 5 touchdowns and 1 interception this season, while Christian McCaffrey has accumulated 164 total yards and 2 scores.
- Nick Bosa is out for Sunday after injuring his calf in practice, a blow to a 49ers defense already fourth in scoring (10.0 ppg) given Bosa missed all but three games last season.
- Arizona's offense ranks 26th in total yards (272.0 per game) and 24th in scoring (16.5 ppg), with Jacoby Brissett throwing for just 95 yards and an interception in last week's loss to Seattle.
- The 49ers have won six of the past eight head-to-head meetings by an average margin of 19.7 points, though the Cardinals swept the 2024 season series and nearly stole a 16-15 Week 3 game in San Francisco last year.
- Kalshi markets list San Francisco favored by more than 8.5 points at $0.49 (yes) / $0.52 (no) and the over on 47.5 combined points at $0.53, with the platform offering a $55 sign-up bonus via promo code CBSSPORTS55 after a $25 trade.
Why it matters: Kalshi's $0.78 implied probability on the 49ers lines up with San Francisco's top-six scoring offense (31.0 ppg) facing an Arizona unit ranked 24th (16.5 ppg), though the absence of Nick Bosa on a pass rush that produced just four sacks in two games could tighten the spread — currently sitting at 8.5 points.
Ask SkimNews
