Prisco's Week 3 NFL picks: Browns upset Panthers, Giants rally behind Jameis Winston — SkimNews

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- Pete Prisco went 9-7 straight up but a miserable 5-10 ATS in Week 2, leaving his season record at 21-11 SU and 15-17 ATS as he looks to bounce back in Week 3.
- The Cleveland Browns are Prisco's first upset pick, taking +2.5 points at home against Bryce Young's Panthers; he predicts the Browns defense contains Young in a 23-20 win.
- The Tampa Bay Buccaneers (+1.5) are his other contrarian call, upsetting the 2-0 Vikings at home behind a defensive stand against Brian Flores' unit (predicted 21-20).
- Jameis Winston takes over at quarterback for the Giants with Jaxson Dart sidelined; Prisco predicts New York rallies around Winston to beat the 0-2 Titans (predicted 23-14).
- The Chicago Bears are likely to start Case Keenum with both Caleb Williams and Tyson Bagent injured, and Prisco has Philadelphia's defense shutting down the depleted offense (predicted 27-13 Eagles).
- The Washington Commanders turn to Marcus Mariota with Jayden Daniels out, making Seattle a 7-point favorite in Prisco's eyes on the road (predicted 24-13 Seahawks).
- The Miami Dolphins are "playing a lot of young players and building for the future" per Prisco, making the 11.5-point Chiefs spread unsurprising (predicted 28-10 Chiefs).
Why it matters: Prisco's two upset calls — Cleveland (+2.5) and Tampa Bay (+1.5) — directly challenge the spread in two of the week's tightest lines. Three teams (Giants, Bears, Commanders) start backup QBs, and his 15-17 ATS season record entering Week 3 means he's still chasing his Week 1 form after going 5-10 against the spread last week.
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