Week 6 NFL odds, spreads, totals, lines for all 14 games, including Seahawks-Broncos, Packers-Cowboys — SkimNews
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- DraftKings posted spreads, moneylines, and totals for all 14 Week 6 games, with the Seattle Seahawks opening as 2.5-point road favorites at Denver on Thursday Night Football (total 40.5, Broncos +124 ML).
- The Los Angeles Rams are the biggest favorite of the week at -12.5 on the road against the Arizona Cardinals, with the total at 52.5 and the Rams' moneyline at -877.
- The Green Bay Packers are a narrow 1.5-point favorite at Dallas (-115 ML), tying the Giants-Saints (-1.5) and Eagles-Panthers (-1.5) as the tightest spreads on the slate.
- The Jacksonville Jaguars are 2.5-point favorites against the Houston Texans in London, the league's international game of Week 6 (total 42.5).
- The Kansas City Chiefs are 8.5-point road favorites at the Los Angeles Chargers (total 42.5, Chiefs ML -439), while the Buffalo Bills are 6-point road favorites at the Las Vegas Raiders (total 52.5, Bills ML -279).
- The San Francisco 49ers close the week as 7.5-point Monday Night Football favorites at Washington (total 50.5, 49ers ML -424).
- The card is wrapped in affiliate promotions — DraftKings ($290 + NBA League Pass), FanDuel, BetMGM (up to $1,500), Caesars, Fanatics ($350 FanCash), and Kalshi ($55) — signaling the page's commercial as much as informational purpose.
Why it matters: The Rams' 12.5-point road spread is the most lopsided line of Week 6, with the Cardinals priced as the week's biggest underdog (moneyline +596) — a stark contrast to the Packers-Cowboys near pick'em at -1.5, where oddsmakers priced that Sunday night matchup as essentially a coin flip despite Dallas's home field.
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