Missouri vs. Troy odds, picks, predictions: Betting preview, start time for Week 3 college football matchup — SkimNews

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- Missouri hosts Troy at 7 p.m. ET Saturday at Faurot Field at Memorial Stadium as a 27-point favorite, with the over/under set at 49.5, per Fanatics Sportsbook
- Austin Simmons, the Ole Miss transfer quarterback, has thrown for 544 yards and 7 touchdowns with no interceptions through his first two Missouri starts
- Missouri is 2-0 under sixth-year coach Eli Drinkwitz, and its defense has yet to allow an opponent to reach 20 points this season
- Troy arrives at 2-0 under third-year coach Gerad Parker, with the source noting the Trojans' best path to covering the spread is ball control to limit Missouri's possessions rather than matching scores score-for-score
- The SportsLine Projection Model has Missouri winning in 99% of its 10,000 simulations and is on a 33-21 run on top-rated college football money-line picks since the 2024 season
- Missouri's running game, built around Jamal Roberts alongside receiver Donovan Olugbode and a largely returning receiving corps, gives the Tigers multiple ways to extend a lead against a smaller Sun Belt front seven
Why it matters: The 27-point spread reflects the real talent gap between an SEC contender and a Sun Belt mid-tier, but its final size hinges on whether Drinkwitz keeps his starters in the full game — the source predicts a businesslike Tigers win with a margin closer to 30 than 50, a frame bettors need to weigh when deciding whether the number is inflated or deserved.
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