Week 6 NFL odds, spreads, totals, lines for every game, including Chargers-Chiefs, Packers-Cowboys — SkimNews
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- Jalen Hurts was placed on injured reserve due to a blood clot, swinging the Eagles' line from -1.5 favorites to 3-point home underdogs against the Panthers (1 p.m. ET kickoff, total 39.5).
- DraftKings lists Week 6 spreads, moneylines, and totals for every game, with headline matchups including Jets-Patriots (-7), Bills-Raiders (+5.5), Chargers-Chiefs (-7.5), and Cowboys-Packers (-1.5).
- The Los Angeles Rams are the heaviest favorite of the slate at -12.5 over the Cardinals, with a moneyline of -750 and total of 51.5.
- Four Week 6 totals sit at 41.5 or below — Eagles-Panthers (39.5), Buccaneers-Steelers (38.5), Browns-Ravens (39.5), and Chiefs-Chargers (41.5) — with bookmakers pricing in defensive, low-scoring games.
- The Colts (-7 vs. Titans) and Patriots (-7.5 vs. Jets) carry identical moneylines of -340, signaling comparable confidence from oddsmakers in each road favorite.
- The SportsLine Projection Model is publishing separate betting projections for all 14 Week 6 matchups spanning Sunday and Monday, including 49ers-Commanders on Monday Night Football (-7.5).
- Promo codes from DraftKings ($200 bonus + NBA League Pass), Caesars, Kalshi, BetMGM ($1,500 bonus), and Fanatics ($350 FanCash) are threaded into the odds listings to drive new-user sign-ups.
Why it matters: The Eagles' 4.5-point swing (from -1.5 to +3) tied directly to Hurts' injured reserve placement is the single most consequential line movement of the week and reshapes every Philadelphia-related bet. Four matchups carrying totals of 41.5 or lower signals oddsmakers expect an unusually defensive Week 6 slate.
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