Iowa vs. Washington prediction, odds, time: Week 6 college football Friday picks by proven model — SkimNews

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- Iowa enters at 4-1 overall and 1-1 in Big Ten play following a 31-14 home loss to Ohio State, the Hawkeyes' first defeat of the season
- Iowa QB Hank Brown is questionable with an AC joint sprain, putting backup Jeremy Hecklinski in line for his first significant road start
- Washington sits at 3-2 overall and 0-2 in Big Ten play, paced by QB Demond Williams Jr. (1,327 passing yards, 8 TDs), though Huskies quarterbacks have been sacked 13 times this season
- Washington is listed as a 2.5-point favorite with the over/under at 41.5 and a money line of -148, with kickoff set for 9 p.m. ET at Husky Stadium in Seattle
- SportsLine's model projects exactly 41 total points, making the Under 41.5 the value pick at a 51% hit rate, and also flags one spread side hitting in over 60% of simulations
- Iowa's defense has carried the program, allowing just 12.6 points per game overall and a combined 32 points across its four non-Ohio State opponents, while Washington ranks 34th nationally in yards allowed (84th in yards gained)
Why it matters: Two top-35 defenses collide with both offenses ranking in the bottom half nationally (Iowa 74th, Washington 84th in yards gained), giving the model enough statistical cover to back the Under 41.5. Washington's 0-2 Big Ten start makes this near-must-win territory for the Huskies, while Iowa's QB uncertainty with Brown questionable could force a true road debut for Hecklinski — tilting the game toward whichever defense forces the first mistake.
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