Bills vs. Lions predictions, odds, time: Week 2 'Thursday Night Football' picks by proven model — SkimNews
Get the Sports newsletter
Daily sports — scores, transfers, the storylines from the leagues you actually follow. Free.
- Buffalo Bills opened their season with a 36-31 win over the Houston Texans, led by Josh Allen’s 334 passing yards and two rushing touchdowns
- Detroit Lions edged the New Orleans Saints 31-30 in overtime, powered by Jahmyr Gibbs’ 156 rushing yards and two touchdowns on 29 carries
- SportsLine projection model simulated the Lions vs. Bills game 10,000 times and projects 58 combined points, backing the Over 54.5 in 57% of simulations
- Josh Allen threw for 334 yards and two touchdowns while rushing for two more scores in Week 1, signaling a return to MVP form from his 2024 campaign
- Jahmyr Gibbs carried 29 times for 156 yards and two touchdowns against the Saints, adding five receptions for 30 yards in a dominant all-around performance
- Lions vs. Bills odds list Buffalo as 4.5-point favorites with a total point line of 54.5, up one point from the opening number at betting markets
Why it matters: The SportsLine model has produced a 53-39 record on top-rated NFL picks since 2024, giving its Over call and spread lean measurable weight for bettors allocating capital in Week 2. With both offenses clicking and key players exceeding individual totals, the projected 58-point output creates actionable value against the posted line.
Ask SkimNews
