Colts vs. Commanders predictions, odds, time: 2026 Week 4 NFL London game picks from proven model — SkimNews
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- Colts vs. Commanders meet at Tottenham Hotspur Stadium in London on Sunday at 9:30 a.m. ET in Week 4, with Indianapolis installed as a 4.5-point favorite and the over/under set at 46.5
- SportsLine's model, which simulates every NFL game 10,000 times, projects 52 combined points and has the Over 46.5 hitting in 59% of simulations, with the model on a 54-43 run on top-rated picks since 2024
- The Colts' defense ranks dead-last in the NFL in yards allowed while Washington ranks 27th, and both teams are allowing more than 30 points per game — only the Lions have given up more
- Jonathan Taylor paces the Colts' rushing attack with 258 yards and four touchdowns this season, while Washington's receiver duo of Terry McLaurin (questionable, hamstring) and Stefon Diggs have combined for 276 yards and four TDs
- Washington enters without starting quarterback Jayden Daniels, who remains out with an elbow injury after the Commanders upset the reigning Super Bowl champion Seahawks in Week 3
- The Over has hit in all three Commanders games and two of three Colts games so far in 2026, supporting the model's projection
Why it matters: Bettors have a model-backed edge in a matchup featuring two of the NFL's worst defenses — both allowing over 30 PPG with Indianapolis dead-last in yards. The Over has already hit in all three Commanders games and two of three Colts games this season. Indianapolis laying 4.5 at a neutral London site adds spread risk for Colts backers.
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