Iowa State vs. BYU prediction, odds, time: Week 6 college football Friday picks from proven model — SkimNews
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- BYU Cougars (4-0, 2-0 Big 12) host Iowa State at 10:15 p.m. ET at LaVell Edwards Stadium, listed as 11.5-point favorites with a -469 money line and a 46.5-point over/under.
- Iowa State Cyclones (3-2, 1-1 Big 12) are 0-2 against ranked opponents and 0-1 on the road this season, coming off a 45-42 win over West Virginia, while BYU is 2-0 at home and has outscored opponents 149-57.
- SportsLine's model simulated the game 10,000 times and projects 52 combined points, making the Over 45.5 an A-rated pick that hits 63% of the time; the model also has a spread side hitting over 50% of simulations.
- BYU sophomore quarterback Bear Bachmeier has completed 64% of his passes for 704 yards and six touchdowns with one interception, adding 130 rushing yards and four rushing TDs on 27 carries.
- Iowa State senior quarterback Jaylen Raynor has completed 58% of passes for 903 yards, six touchdowns, and four interceptions through five games.
- Iowa State leads the all-time series 5-1, but BYU won last year's meeting in Iowa — a split fact the dominant BYU-favored framing partially obscures by emphasizing BYU's unbeaten home record.
- The model entered Week 6 on a 40-35 run on top-rated college football picks, per SportsLine.
Why it matters: Bettors following SportsLine's model — up 5 units on the season at 40-35 on top-rated CFB picks — get a 63%-confidence Over recommendation and a spread lean on a Friday night game where BYU's undefeated home form and 11.5-point spread clash with Iowa State's 0-2 mark against ranked opponents, making line value the central question rather than upset potential.
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